- 5-Hydroxy-2-adamantanone
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- $0.00 / 1kg
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2024-08-26
- CAS:20098-14-0
- Min. Order: 1kg
- Purity: 98%+
- Supply Ability: 1000kg per Month
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| 5-Hydroxyadamantan-2-one Basic information |
| 5-Hydroxyadamantan-2-one Chemical Properties |
Melting point | >300 °C (lit.) | Boiling point | 296.5±33.0 °C(Predicted) | density | 1.301±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | solubility | DMSO, Methanol | form | Crystalline Powder | pka | 14.69±0.20(Predicted) | color | White to off-white | InChI | InChI=1S/C10H14O2/c11-9-7-1-6-2-8(9)5-10(12,3-6)4-7/h6-8,12H,1-5H2 | InChIKey | TZBDEVBNMSLVKT-RIKBPLFRSA-N | SMILES | C12CC3(O)CC(CC(C3)C1=O)C2 | CAS DataBase Reference | 20098-14-0(CAS DataBase Reference) |
| 5-Hydroxyadamantan-2-one Usage And Synthesis |
Description |
5-Hydroxy-2-adamantanone (5-hydroxyadamantan-2-one) is a versatile starting material for synthesising various 2,5- or 1,4-disubstituted adamantanes. Chemical methods for synthesizing 5-hydroxy-2-adamantanone include disproportionation of 2-hydroxyadamantane and oxidation of 2-adamantanone. A synthetic approach to produce 5-hydroxy-2-adamantanone using P450cam (CYP101A1; a camphor monooxygenase) coupled with NADH regeneration as an oxidation biocatalyst has been reported[1].
| Chemical Properties | White crystal or crystalline powder | Uses | 5-Hydroxy-2-adamantanone may be used in the following studies:
- As a model compound to investigate the application of lanthanide NMR shift reagents for the analysis of disubstituted derivative of adamantane.
- As a starting material for the synthesis of E-2-amino-5-hydroxyadamantane.
- As a starting material for the synthesis of 4-(triphenylsilyloxy)adamantan-1-ol.
| Uses | anthelmintic | Definition | ChEBI: Idramantone is a member of adamantanones. | Brand name | INDICLOR (Nycomed
Amersham). | General Description | 5-Hydroxy-2-adamantanone is a disubstituted derivative of adamantane. The biocatalyzed synthesis of 5-hydroxy-2-adamantanone from 2-adamantanone has been investigated. | References | [1] Toshiki Furuya . “Biocatalytic production of 5-hydroxy-2-adamantanone by P450cam coupled with NADH regeneration.” Journal of Molecular Catalysis B-enzymatic 94 (2013): Pages 111-118.
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| 5-Hydroxyadamantan-2-one Preparation Products And Raw materials |
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