Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:6β-Prostaglandin I1 CAS:62770-50-7 Purity:>98% Package:1mg;10mg;50mg;100mg;
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:6β-Prostaglandin I1 CAS:62770-50-7 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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Tel: |
021-65675885 18964387627 |
Email: |
customer_service@efebio.com |
Products Intro: |
Product Name:6β-Prostaglandin I1 CAS:62770-50-7 Purity:99% Package:1mg;5mg;10mg
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:6β-Prostaglandin I1 CAS:62770-50-7 Purity:详情请点击官网 Package:1 mg
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| 5,6BETA-DIHYDRO PGI2 Basic information |
Product Name: | 5,6BETA-DIHYDRO PGI2 | Synonyms: | 6BETA-PROSTAGLANDIN I1;6S,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;5,6BETA-DIHYDRO PGI2;5,6-dihydroprostacyclin;(6S,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;RJADQDXZYFCVHV-CBIPHORWSA-N;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6S,9α,11α,13E,15S)- (9CI);6β-Prostaglandin I1 | CAS: | 62770-50-7 | MF: | C20H34O5 | MW: | 354.48 | EINECS: | | Product Categories: | | Mol File: | 62770-50-7.mol | ![5,6BETA-DIHYDRO PGI2 Structure](CAS/GIF/62770-50-7.gif) |
| 5,6BETA-DIHYDRO PGI2 Chemical Properties |
storage temp. | Store at -20°C | solubility | DMF: >10 mg/ml; DMSO: >5 mg/ml; Ethanol: >20 mg/ml; PBS pH 7.2: >80 μg/ml | form | A crystalline solid |
| 5,6BETA-DIHYDRO PGI2 Usage And Synthesis |
Description | 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.1,2 | Definition | ChEBI: 6-Prostaglandin I1 is a prostanoid. | References | 1. Whittle, B.J.R., Moncada, S., Whiting, F., et al. Carbacyclin — a potent stable prostacyclin analogue for the inhibition of platelet aggregation Prostaglandins 19(4),605-627(1980). 2. Blair, I.A., Hensby, C.N., and MacDermot, J. Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: Prostanoid structure-activity relationships Br. J. Pharmac. 69(3),519-525(1980). |
| 5,6BETA-DIHYDRO PGI2 Preparation Products And Raw materials |
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