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| | Chlorotripyrrolidinophosphonium hexafluorophosphate Basic information |
| Product Name: | Chlorotripyrrolidinophosphonium hexafluorophosphate | | Synonyms: | PyClOP,ChlorotripyrrolidinophosphoniuMhexafluorophosphat;chlorotri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V);Chlorotripyrrolidinophosphonium hexafluorophosphate98+%;Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate;PYCLOP;CHLOROTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;Chlorotripyrrolidinophosphoniumhexafluorophosphat;PYCLOP CHLOROTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE | | CAS: | 133894-48-1 | | MF: | C12H24ClF6N3P2 | | MW: | 421.73 | | EINECS: | 628-539-2 | | Product Categories: | | | Mol File: | 133894-48-1.mol |  |
| | Chlorotripyrrolidinophosphonium hexafluorophosphate Chemical Properties |
| Melting point | 145-148°C | | storage temp. | 2-8°C | | solubility | soluble in Chloroform, Methanol | | form | Crystalline Powder | | color | White to yellow | | Sensitive | Moisture Sensitive | | BRN | 6842341 | | InChIKey | BSCYRXJVGSZNKX-UHFFFAOYSA-N | | CAS DataBase Reference | 133894-48-1(CAS DataBase Reference) |
| | Chlorotripyrrolidinophosphonium hexafluorophosphate Usage And Synthesis |
| Uses | Crystalline reagent for peptide coupling of a-alkylated N-Fmoc and N-Z-amino acids in high yield and without racemization. | | Uses | Reagent for:
Peptide coupling reactions and synthesis of coupling reagents
Sequence selective peptide recognition
Synthesis of condensing reagents
Synthesis of heterocyclic β-sheet ligands | | Preparation | Preparation of chlorotripyrrolidinophosphonium hexafluorophosphate: addition of chlorine to a diethyl ether solution of tripyrrolidinophosphine, then addition of KPF6 in water. Addition of tripyrrolidinophosphine oxide to a DCM solution of phosphoryl trichloride, then addition of KPF6 in water. | | reaction suitability | reaction type: Coupling Reactions |
| | Chlorotripyrrolidinophosphonium hexafluorophosphate Preparation Products And Raw materials |
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