N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine manufacturers
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| N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Basic information |
| N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Chemical Properties |
density | 1.29±0.1 g/cm3(Predicted) | pka | 9.45±0.43(Predicted) | InChIKey | SWIWEMMZHYDBHD-XZWHSSHBSA-N | SMILES | C(NC1=NC(OCCC#N)=C2C(=N1)N([C@@H]1O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C1)C=N2)(=O)C(C)C |
| N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Usage And Synthesis |
Description | N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine is a nucleoside, ribonucleoside, and anti-cancer drug. It is modified with two acyl groups at the 2′ position of the sugar moiety and contains a phosphoramidite group in the 5′ position. It is an activator of DNA synthesis in vitro. In vivo studies have shown that N2-Isobutyryl O6 cyanoethyl 7' OH N trityl morpholino guanine can be used as an anticancer agent against human breast cancer cells. |
| N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine Preparation Products And Raw materials |
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