腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂
| 中文名称 | 腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂 |
|---|---|
| 中文同义词 | 腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂;腺苷酰基亚胺二磷酸四锂盐;5'-腺苷酸,用咪啶硫磷酸,单酐,TETRALITHIUM盐;AMP PNP,KIR6阻滞剂 |
| 英文名称 | ADENYLYL-IMIDODIPHOSPHATE, TETRALITHIUM SALT |
| 英文同义词 | AMP-PNP, 4LI;AMP-PNP, LI4;AMP-PNP LITHIUM SALT;AMP-PNP TETRALITHIUM SALT;ADRENOSINE 5'-(BETA,GAMMA-IMIDO)TRIPHOSPHATE TETRALITHIUM SALT;ADENOSINE 5'-(BETA,GAMMA-IMIDO)TRIPHOSPHATE, TETRALITHIUM SALT;ADENYLYL-IMIDODIPHOSPHATE, TETRALITHIUM;ADENYLYL-IMIDODIPHOSPHATE, TETRALITHIUM SALT |
| CAS号 | 72957-42-7 |
| 分子式 | C10H18LiN6O12P3 |
| 分子量 | 514.15 |
| EINECS号 | 277-127-5 |
| 相关类别 | |
| Mol文件 | 72957-42-7.mol |
| 结构式 |  |
腺苷-5'-(Β,Γ-亚氨基)三磷酸四锂 性质
| 熔点 | >225°C (dec.) |
|---|---|
| 储存条件 | −20°C |
| 溶解度 | H2O:50 mg/mL |
| 形态 | 粉末 |
| 颜色 | 白色 |
| 水溶解性 | 26.5mg/ml in water |
| 稳定性 | 吸湿性 |
AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) 是 ATP 不可水解的类似物，可抑制 KATP 通道。
AMP-PNP (5 to 500 μM; Li salt) reduced the open-probability p
o
of K
ATP
channels and decreases the single-channel currents at high nucleotide concentrations by approximately 10%.
AMP-PNP inhibits K
ATP
channels of ventricular myocytes and of pancreatic β-cells both in the absence and presence of Mg
2+
ions.