- 4-Phenylbutanol
-
- $30.00 / 1kg
-
2024-08-15
- CAS:3360-41-6
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20 tons
- 4-Phenylbutan-1-ol
-
- $1.00 / 1KG
-
2024-04-24
- CAS:3360-41-6
- Min. Order: 1KG
- Purity: 99.91%
- Supply Ability: 200000
- 4-Phenylbutanol
-
- $0.00 / 1KG
-
2023-09-06
- CAS:3360-41-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
|
| 4-Phenylbutanol Basic information |
| 4-Phenylbutanol Chemical Properties |
Boiling point | 140-142 °C14 mm Hg(lit.) | density | 0.984 g/mL at 20 °C(lit.) | refractive index | n20/D 1.521(lit.) | Fp | >230 °F | storage temp. | Sealed in dry,Room Temperature | solubility | Almost insoluble in water, soluble in alcohol and oils | form | Liquid | pka | 15.13±0.10(Predicted) | color | Clear colorless | Odor | Sweet, but rather heavy, herbaceous-rosy odor | Odor Type | floral | BRN | 2042122 | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | InChIKey | LDZLXQFDGRCELX-UHFFFAOYSA-N | LogP | 2.350 | CAS DataBase Reference | 3360-41-6(CAS DataBase Reference) | NIST Chemistry Reference | Benzenebutanol(3360-41-6) | EPA Substance Registry System | Benzenebutanol (3360-41-6) |
| 4-Phenylbutanol Usage And Synthesis |
Chemical Properties | colourless liquid | Uses | 4-Phenyl-1-butanol was used in synthesis of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. | Uses | 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases. | Production Methods | 4-Phenylbutanol can be produced 1) from Phenylacetaldehyde and Acetaldehyde by condensation, followed by hydrogenation and reduction of the unsaturated aldehyde.
2) from Phenylethyl magnesiumbromide plus
Ethylene oxide in a Grignard type reaction. | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 31, p. 2607, 1983 DOI: 10.1248/cpb.31.2607 Journal of the American Chemical Society, 73, p. 124, 1951 DOI: 10.1021/ja01145a045 | General Description | 4-Phenyl-1-butanol is oxidized by ceric ammonium nitrate in acetonitrile to afford 2-phenyltetrahydrofuran. It undergoes cyclization in presence of phosphoric acid at high temperature to yield tetralin. |
| 4-Phenylbutanol Preparation Products And Raw materials |
|