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| | 20-HETE Basic information |
| Product Name: | 20-HETE | | Synonyms: | 20-HETE, 20-Hydroxyarachidonic acid;20-HETE Lipid Maps MS Standard;20-Hydroxyeicosa-5Z,8Z,11Z,14Z-tetraenoic acid;20-HYDROXY-(5Z,8Z,11Z,14Z)-EICOSATETRAENOIC ACID;20-HYDROXYARACHIDONIC ACID;20-HETE;20-Hydroxyarachlidonic acid;(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid | | CAS: | 79551-86-3 | | MF: | C20H32O3 | | MW: | 320.47 | | EINECS: | | | Product Categories: | | | Mol File: | 79551-86-3.mol |  |
| | 20-HETE Chemical Properties |
| Boiling point | 482.0±33.0 °C(Predicted) | | density | 0.985±0.06 g/cm3(Predicted) | | Fp | 14℃ | | storage temp. | -20°C | | solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | | form | Powder | | pka | 4.75±0.10(Predicted) |
| | 20-HETE Usage And Synthesis |
| Uses | 20-HETE is a cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature. | | Definition | ChEBI: A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20. | | Biochem/physiol Actions | 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid (20-HETE) is an arachidonic acid metabolite via cytochrome P4504A, that is an activator of the Ras/MAP (microtubule-associated protein) pathway. 20-HETE acid is a predominant arachidonic acid present in the kidney. It is involved in the regulation of sodium, potassium and chloride transport in the renal tubules. 20-HETE is often excreted in urine in the form of glucuronide conjugate and sometimes as free acids. Increased urine 20-HETE is observed during pregnancy in rats. |
| | 20-HETE Preparation Products And Raw materials |
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