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LE 300

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LE 300 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:LE 300
CAS:274694-98-3
Purity:98.35% Package:1mg;108USD|5mg;263USD|10mg;388USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:LE 300
CAS:274694-98-3
Purity:95% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:LE 300
CAS:274694-98-3
Purity:>=98%(HPLC) Package:$215.9/10mg;Bulk package Remarks:98%(HPLC)
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:LE 300;6,7,8,9,14,15-Hexahydro-7-Methyl-5H-indolo[3,2-f][3]benzazecine
CAS:274694-98-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Products Intro: Product Name:LE 300
CAS:274694-98-3
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g

LE 300 manufacturers

  • LE 300
  • LE 300 pictures
  • $89.00 / 1mg
  • 2024-11-19
  • CAS:274694-98-3
  • Min. Order:
  • Purity: 98.35%
  • Supply Ability: 10g
LE 300 Basic information
Product Name:LE 300
Synonyms:7-METHYL-6,7,8,9,14,15-HEXAHYDRO-5H-BENZ[D]INDOLO[2,3-G]AZECINE;6,7,8,9,14,15-HEXAHYDRO-7-METHYL-5H-INDOLO[3,2-F][3]BENZAZECINE;6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f]benzazecine;LE 300;5H-Indolo[3,2-f][3]benzazecine, 6,7,8,9,14,15-hexahydro-7-methyl-
CAS:274694-98-3
MF:C20H22N2
MW:290.4
EINECS:
Product Categories:Dopamine receptor
Mol File:274694-98-3.mol
LE 300 Structure
LE 300 Chemical Properties
Melting point >91°C (dec.)
storage temp. Store at RT
solubility DMSO: 26 mg/mL
form solid
color Off-White to Pale Beige
Stability:Hygroscopic
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
LE 300 Usage And Synthesis
DescriptionLE300 is a dopamine D1-like receptor antagonist (Kis = 1.9 and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively) and antagonist of the serotonin (5-HT) receptor subtype 5-HT2A (pA2 = 8.32 in a rat tail artery assay). It is selective for dopamine D1 and D5 over D2L and D4.4 receptors (Kis = 44.7 and 109 nM, respectively). LE300 inhibits the conditioned avoidance response in the pole-jump test in rats (ED50 = 0.94 mg/kg), which is predictive for antipsychotic-like activity. It also reduces locomotor activity in the open field test in rats (ED50 = 0.74 mg/kg).
UsesLE 300 is a potent and selective dopamine receptor antagonist.
DefinitionChEBI: LSM-2007 is a member of indoles.
Biological ActivityPotent and selective dopamine D 1 receptor antagonist (K i values are 0.08-1.9 nM and 6-45 nM for D 1 and D 2 receptors respectively). Also displays moderate affinity for the 5-HT 2A receptor (K i = 20 nM). Active in vivo .
storageRoom temperature
LE 300 Preparation Products And Raw materials
Tag:LE 300(274694-98-3) Related Product Information
Vanoxerine dihydrochloride (RS)-TRANS-7-HYDROXY-2-[N-PROPYL-N-(3'-IODO-2'-PROPENYL)AMINO]TETRALIN MALEATE Clozapine REMOXIPRIDE HYDROCHLORIDE CLOTHIAPINE BTCP HCL (+)-AJ 76 HYDROCHLORIDE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Bromocriptine mesylate 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol U-99194 MALEATE LE 300