LE 300

LE 300 Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354 +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:LE 300 CAS:274694-98-3 Purity:98.35% Package:1mg;108USD\|5mg;263USD\|10mg;388USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Wuhan Topule Biopharmaceutical Co., Ltd
Tel:	+8618327326525
Email:	masar@topule.com
Products Intro:	Product Name:LE 300 CAS:274694-98-3 Purity:95% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:LE 300 CAS:274694-98-3 Purity:>=98%(HPLC) Package:$215.9/10mg;Bulk package Remarks:98%(HPLC)

Company Name:
Tel:	821-50328103-801 18930552037
Email:	3bsc@sina.com
Products Intro:	Product Name:LE 300;6,7,8,9,14,15-Hexahydro-7-Methyl-5H-indolo[3,2-f][3]benzazecine CAS:274694-98-3 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g

Company Name:	EMMX Biotechnology LLC
Tel:	888-539-0666
Email:	info@emmx.com
Products Intro:	Product Name:LE 300 CAS:274694-98-3 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g

LE 300 manufacturers

LE 300 Basic information

Product Name:	LE 300
Synonyms:	7-METHYL-6,7,8,9,14,15-HEXAHYDRO-5H-BENZ[D]INDOLO[2,3-G]AZECINE;6,7,8,9,14,15-HEXAHYDRO-7-METHYL-5H-INDOLO[3,2-F][3]BENZAZECINE;6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f]benzazecine;LE 300;5H-Indolo[3,2-f][3]benzazecine, 6,7,8,9,14,15-hexahydro-7-methyl-
CAS:	274694-98-3
MF:	C20H22N2
MW:	290.4
EINECS:
Product Categories:	Dopamine receptor
Mol File:	274694-98-3.mol

LE 300 Chemical Properties

Safety Information

WGK Germany

MSDS Information

Provider	Language
SigmaAldrich	English

LE 300 Usage And Synthesis

Description	LE300 is a dopamine D₁-like receptor antagonist (K_is = 1.9 and 7.5 nM in CHO cell membranes expressing human dopamine D₁ and D₅ receptors, respectively) and antagonist of the serotonin (5-HT) receptor subtype 5-HT_2A (pA₂ = 8.32 in a rat tail artery assay). It is selective for dopamine D₁ and D₅ over D_2L and D_4.4 receptors (K_is = 44.7 and 109 nM, respectively). LE300 inhibits the conditioned avoidance response in the pole-jump test in rats (ED₅₀ = 0.94 mg/kg), which is predictive for antipsychotic-like activity. It also reduces locomotor activity in the open field test in rats (ED₅₀ = 0.74 mg/kg).
Uses	LE 300 is a potent and selective dopamine receptor antagonist.
Definition	ChEBI: LSM-2007 is a member of indoles.
Biological Activity	Potent and selective dopamine D 1 receptor antagonist (K i values are 0.08-1.9 nM and 6-45 nM for D 1 and D 2 receptors respectively). Also displays moderate affinity for the 5-HT 2A receptor (K i = 20 nM). Active in vivo .
storage	Room temperature

LE 300 Preparation Products And Raw materials

Tag:LE 300(274694-98-3) Related Product Information

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