| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:YM 976;4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyriMidin-2(1H)-one
CAS:191219-80-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Basic information |
| Product Name: | 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE | | Synonyms: | YM 976;4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE;4-(3-Chloro-phenyl)-1,7-diethyl-1H-pyrido[2,3-d]pyrimidin-2-one;Pyrido[2,3-d]pyrimidin-2(1H)-one, 4-(3-chlorophenyl)-1,7-diethyl-;YM-976,Phosphodiesterase (PDE),PDE4 inhibitor,inhibit,phosphodiesterase 4,anti-inflammatory activities,antigen-induced airway responses,Inhibitor,YM976,YM 976 | | CAS: | 191219-80-4 | | MF: | C17H16ClN3O | | MW: | 313.78 | | EINECS: | | | Product Categories: | Cyclic Nucleotide related | | Mol File: | 191219-80-4.mol | ![4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Structure](CAS/GIF/191219-80-4.gif) |
| | 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Chemical Properties |
| Melting point | 132.7-134.0 °C(lit.) | | Boiling point | 485.4±55.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMSO: 16 mg/mL | | form | solid | | pka | 2.11±0.20(Predicted) | | color | pale yellow |
| | 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Usage And Synthesis |
| Uses | YM 976 is an inhibitor of PDE4. | | Definition | ChEBI: 4-(3-chlorophenyl)-1,7-diethyl-2-pyrido[2,3-d]pyrimidinone is a member of pyrimidines. | | Biological Activity | Orally active PDE4 inhibitor (IC 50 = 2.2 nM). Low emetogenic activity, suggested to be due to poor brain penetration. |
| | 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE Preparation Products And Raw materials |
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