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| | Fomc-Gly-Gly-Phe-Gly-OH Basic information |
| Product Name: | Fomc-Gly-Gly-Phe-Gly-OH | | Synonyms: | Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanyl-;(((9H-Fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanylglycine;Fmoc-GGFG;Fmoc-GGFG-OH;(S)-2-[2-[2-[2-(Fmoc-amino)acetamido]acetamido]-3-phenylpropanamido]acetic Acid;Fomc-Gly-Gly-Phe-Gly;Fomc-Gly-Gly-Phe-Gly-OH | | CAS: | 1817857-75-2 | | MF: | C30H30N4O7 | | MW: | 558.58 | | EINECS: | | | Product Categories: | | | Mol File: | 1817857-75-2.mol |  |
| | Fomc-Gly-Gly-Phe-Gly-OH Chemical Properties |
| Boiling point | 980.0±65.0 °C(Predicted) | | density | 1.329±0.06 g/cm3(Predicted) | | pka | 3.32±0.10(Predicted) | | form | Solid | | color | White to off-white | | InChIKey | LCOCGQVZUSLQJD-VWLOTQADSA-N | | SMILES | C(O)(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| | Fomc-Gly-Gly-Phe-Gly-OH Usage And Synthesis |
| Uses | Fomc-Gly-Gly-Phe-Gly-OH, also known as FMOC-GGFG-OH or 2-[[(2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid, can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit | | Definition | Fomc-gly-gly-ph-gly-OH contains several functional groups. The Fmoc group is a commonly used protective group in peptide synthesis and is often used to protect N-terminal amino groups. Gly-Gly-Phe-Gly is glycyl-glycyl-phenylalanyl-glycine (GGFG) peptide which can be linked to other groups (drug) through cysteine residues. This tetrapeptide linker is protease-cleavable.
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| | Fomc-Gly-Gly-Phe-Gly-OH Preparation Products And Raw materials |
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