- Canadine
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- $0.00 / 20mg
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2023-02-24
- CAS:5096-57-1
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| canadine Basic information |
Product Name: | canadine | Synonyms: | (13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine;(S)-Canadine;(S)-Tetrahydroberberine;C03329;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-;(-)-Canadine | CAS: | 5096-57-1 | MF: | C20H21NO4 | MW: | 339.39 | EINECS: | 225-815-0 | Product Categories: | | Mol File: | 5096-57-1.mol | ![canadine Structure](CAS/GIF/5096-57-1.gif) |
| canadine Chemical Properties |
Melting point | 135° | alpha | D22 -308°; -317° (c = 0.28; 0.4, both in methanol) | Boiling point | 475.36°C (rough estimate) | density | 1.2270 (rough estimate) | refractive index | 1.6000 (estimate) | storage temp. | Refrigerator | solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated) | form | Solid | pka | 6.53±0.20(Predicted) | color | Pale Yellow to Light Yellow |
RIDADR | 1544 | HazardClass | 6.1(b) | PackingGroup | III |
| canadine Usage And Synthesis |
Chemical Properties | Yellow Solid | Uses | (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents. | Definition | ChEBI: (S)-canadine is the (S)-enantiomer of canadine. It has a role as a plant metabolite. It is functionally related to a (S)-nandinine. It is an enantiomer of a (R)-canadine. | target | P450 (e.g. CYP17) |
| canadine Preparation Products And Raw materials |
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