吲达尼定
| 中文名称 | 吲达尼定 |
|---|---|
| 中文同义词 | 吲达尼定;化合物 T11651 |
| 英文名称 | Indanidine |
| 英文同义词 | Indanidine;N-(2-Imidazolin-2-yl)-2-methyl-2H-indazol-4-amine;N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine;2H-Imidazole, 4-(2-imidazolin-2-ylamino)-2-methyl-;4-(2-Imidazolin-2-ylamino)-2-methyl-2H-imidazole;Indanidine [inn];Indanidinum;Unii-mp564ife34 |
| CAS号 | 85392-79-6 |
| 分子式 | C11H13N5 |
| 分子量 | 215.25 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 85392-79-6.mol |
| 结构式 |  |
吲达尼定 性质
| 沸点 | 413.3±37.0 °C(Predicted) |
|---|---|
| 密度 | 1.40±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 8.83±0.10(Predicted) |
Indanidine 是一种 α-肾上腺素能激动剂。
alpha-adrenergic
The selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo.