| Company Name: |
Shanghai Tauto Biotech Co., Ltd.
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| Tel: |
021-51320588 |
| Email: |
tauto@tautobiotech.com |
| Products Intro: |
Product Name:Phallacidin
CAS:26645-35-2
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:P2303
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Phallacidin
CAS:26645-35-2
Purity:>= 85 % Package:1mg Remarks:P8157
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| | PHALLACIDIN Basic information |
| Product Name: | PHALLACIDIN | | Synonyms: | 5-Dihydroxy-Leu-Val-erythro-3-Hydroxy-D-Asp-Cys-cis-4-Hydroxy-Pro);Cyclo(Ala-2-Mercapto-Trp-4;PHALLACIDIN FROM AMANITA PHALLOIDES;CYCLO(ALA-2-MERCAPTO-TRP-4;5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO);PHALLACIDIN;PHALLICIDIN;CYCLO[ALA-2-MERCAPTO-TRP-4,5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO];-3-hydroxy-d-alpha-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl)cyclic(2-6)-s;cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro | | CAS: | 26645-35-2 | | MF: | C37H50N8O13S | | MW: | 846.9 | | EINECS: | | | Product Categories: | marker | | Mol File: | 26645-35-2.mol |  |
| | PHALLACIDIN Chemical Properties |
| density | 1.1678 (rough estimate) | | refractive index | 1.7400 (estimate) | | solubility | DMF: Soluble; DMSO: Soluble; Methanol: Soluble; Water: Soluble | | form | White to off-white powder. |
| Hazard Codes | T+ | | Risk Statements | 26/27/28 | | Safety Statements | 22-36/37/39-45 | | RIDADR | 1544 | | WGK Germany | 3 | | RTECS | GT8943000 | | HazardClass | 6.1(a) | | PackingGroup | I | | HS Code | 2934999090 |
| | PHALLACIDIN Usage And Synthesis |
| Description | Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds filamentous actin (F-actin) like phalloidin , but contains a carboxyl group for coupling reactions. | | Uses | Phallacidin is a natural mycotoxin first isolated from the death cap mushroom. It binds filamentous actin like phalloidin. | | Uses | Toxin Phallacidin is a weak fluorescent bicyclic peptide probe in aquous solution, Which is isolated from Amanita phalloides mushroom and could be used for blocking F-actin staining by labeled phallotoxins, which promotes actin polymerization. | | Definition | ChEBI: A homodetic bicyclic heptapeptide having a sulfide bridge. | | Biochem/physiol Actions | Phallacidin, which is a bicyclic toxin from the Amanita phalloides mushroom, has been shown to inhibit F-actin degradation by proteolytic enzymes including trypsin and α-chymotrypsin. | | Enzyme inhibitor | This cyclic heptapeptide toxin (FWfree-acid = 846.92 g/mol; CAS 26645-35-2) from the poisonous green fungus Amanita phalloides stabilizes actin filaments and inhibits actin filament depolymerization. NBD phallacidin is a high-affinity, filamentous actin probe consisting of rabbit actin that is conjugated by reacting its thiol group with 4-chloro-7- nitrobenzofurazan, a yellow-green fluorescent dye. NBD phallacidin (Excitation at 465 nm; Emission at 536 nm) selectively stains F-actin un a manner that is superior to antibody staining, preferably in fixed and permeabilized samples. See Phalloidin |
| | PHALLACIDIN Preparation Products And Raw materials |
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