| Company Name: |
VDM Biochemicals
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| Tel: |
0330-2528181 |
| Email: |
sales@vdmbio.com |
| Products Intro: |
Product Name:9-Hydroxyellipticine, Hydrochloride
CAS:52238-35-4
Purity:>=95%
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| Company Name: |
Aikon International Limited
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| Tel: |
025-66113011 18112977050 |
| Email: |
sales01@aikonchem.com |
| Products Intro: |
Product Name:5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol hydrochloride
CAS:52238-35-4
Purity:95+% Package:1g;5g;10g
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| | Nsc264136 Basic information |
| Product Name: | Nsc264136 | | Synonyms: | Nsc264136;9-Hydroxyellipticine, Hydrochloride;9-hydroxyellipticine HCl salt;5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol hydrochloride;9Hydroxyellipticine hydrochloride,9 Hydroxyellipticine hydrochloride | | CAS: | 52238-35-4 | | MF: | C17H15ClN2O | | MW: | 298.7668 | | EINECS: | | | Product Categories: | Other Enzyme Inhibitors and Activators. | | Mol File: | 52238-35-4.mol |  |
| | Nsc264136 Chemical Properties |
| Melting point | >223oC (dec.) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly, Heated), Methanol (Slightly, Sonicated) | | form | Solid | | color | Orange to Dark Orange |
| | Nsc264136 Usage And Synthesis |
| Description | 9-Hydroxyellipticine is a derivative of ellipticine with diverse biological activities. It inhibits aroclor-induced activation of aniline hydroxylase, aminopyrine N-demethylase, and 7-ethoxycourmarin O-deethylase in rat liver microsomes (Kis = 3.5, 0.6, and 0.74 μM, respectively). 9-Hydroxyellipticine inhibits the growth of L1210 murine leukemia cells (IC50 = 3 nM) in vitro and increases survival in an L1210 mouse leukemia model. It inhibits carrageenan-induced edema and UV-induced erythema in guinea pigs. | | Uses | 9-Hydroxyellipticine Hydrochloride is a potent topoisomerase II inhibitor. |
| | Nsc264136 Preparation Products And Raw materials |
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