| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:4-Methylaminoantipyrine hydrochloride
CAS:856307-27-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310 |
| Email: |
3003867561@qq.com |
| Products Intro: |
Product Name:Antipyrine,4-(methylamino)-, hydrochloride
CAS:856307-27-2
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg
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| | MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Basic information |
| Product Name: | MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl | | Synonyms: | MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl;3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-, hydrochloride;4-Methylamino-1,5-dimethyl-2-phenyl;N-Methyl-4-aminoantipyrine Hydrochloride;4-Methylaminoantipyrine hydrochloride;Metamizole EP Impurity C HCl;Antipyrine,4-(methylamino)-, hydrochloride;4-Methylaminophenazone Hydrochloride | | CAS: | 856307-27-2 | | MF: | C12H16ClN3O | | MW: | 253.73 | | EINECS: | | | Product Categories: | | | Mol File: | 856307-27-2.mol |  |
| | MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Chemical Properties |
| Melting point | >195°C | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly), Water (Slightly) | | form | Solid | | color | Pale Orange to Light Brown | | Stability: | Hygroscopic |
| | MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Usage And Synthesis |
| Uses | 4-Methylaminoantipyrine Hydrochloride is a useful research chemical, a methylamino antipyrine derivatives. | | Biological Activity | 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. It has analgesic, antipyretic and relatively weak anti-inflammatory properties. | | in vitro | Metamizole is a prodrug which, at room temperature and in an atmosphere with oxygen, is spontaneously, nonenzymatically converted to 4-Methylamino antipyrine. Subsequently, the N-methyl side chain of 4-Methylamino antipyrine is oxidized to yield 4-formylaminoantipyrine, which is further converted to 4-aminoantipyrine. Metamizole in aqueous solution and in the presence of oxygen consists of a group of several pyrazolone derivatives of which 4-Methylamino antipyrine is pharmacologically the most important. | | in vivo | The aim of this study is to assess the pharmacokinetics of its active metabolites 4-Methylamino antipyrine in male piglets after a single intramuscular injection of Metamizole. Eight healthy male piglets are administered Metamizole (100 mg/kg) intramuscularly. 4-Methylamino antipyrine plasma concentrations are quantitatively detectable from 0.25 to 48 h. The average maximum concentration of it is of 47.59 mg/mL. The average half-lives is 8.57 h for 4-Methylamino antipyrine. < p> | | target | |
| | MetaMizole IMpurity C (4-MethylaMinoantipyrine) HCl Preparation Products And Raw materials |
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