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| | P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Basic information |
| Product Name: | P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT | | Synonyms: | adenosine5’-(hexahydrogenpentaphosphate),5’.fwdarw.5’-esterwithadenosine,;AP5A;AP5A, 3LI;AP5A, LI3;A(5′)P5(5′)A trilithium salt;P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT;P1,P5-DI(ADENOSINE-5'-PENTAPHOSPHATE), TRILITHIUM;Adenosine 5'-(hexahydrogen pentaphosphate), 5'->5'-ester with adenosine, trilithium salt | | CAS: | 75522-97-3 | | MF: | C20H26Li3N10O22P5 | | MW: | 934.17 | | EINECS: | 278-237-6 | | Product Categories: | Organic-metal salt | | Mol File: | 75522-97-3.mol |  |
| | P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: soluble50mg/mL | | form | powder | | color | white to off-white |
| WGK Germany | 3 | | HS Code | 29349990 |
| | P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Usage And Synthesis |
| Chemical Properties | White powder | | Uses | P1,P5-Di(adenosine-5′) pentaphosphate trilithium salt has been used as a adenylate kinase inhibitor and as a component of pre-AMPPNP rigor solution for treating muscle fibres. | | Biochem/physiol Actions | A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor. |
| | P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE, TRILITHIUM SALT Preparation Products And Raw materials |
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