DBCO-Acid manufacturers
- DBCO-acid
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- $0.00 / 250mg
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2024-03-20
- CAS:1353016-70-2
- Min. Order: 250mg
- Purity: >99.00%
- Supply Ability: 10g
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| | DBCO-Acid Basic information |
| Product Name: | DBCO-Acid | | Synonyms: | DBCO-Acid;Azadibenzocyclooctyne acid;DBCO-(CH2)2-COOH;4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoic acid;11,12-Didehydro-gamma-oxodibenzo[b,f]azocine-5(6H)-butanoic Acid;CAS_1353016-70-2;DBCO acid 1;4-{2-azatricyclo[10.4.0.0?,?]hexadeca-1(12),4(9),5,7,13,15-hexaen-10-yn-2-yl}-4-oxobutanoic acid | | CAS: | 1353016-70-2 | | MF: | C19H15NO3 | | MW: | 305.33 | | EINECS: | | | Product Categories: | ADC LINKER | | Mol File: | 1353016-70-2.mol |  |
| | DBCO-Acid Chemical Properties |
| Melting point | 118-125 °C | | Boiling point | 622.0±55.0 °C(Predicted) | | density | 1.34±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in dimethyl sulfoxide and dimethyl formamide. | | pka | 4.47±0.17(Predicted) | | form | Solid | | color | Off-white to Gray |
| | DBCO-Acid Usage And Synthesis |
| Description | DBCO-Acid is a non-activated building block and adds minimal spacer to modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize amine-containing molecules through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions. | | Uses | DBCO-Acid is a reactant in the synthesis of high-generation polyester dendrimers. Also used in the preparation of modular, plasmin sensitive, clickable poly(ethylene glycol)-heparin-laminin microsphere systems for creating growth factor gradients in peripheral nerve regeneration. | | General Description | Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne click chemistry reactions. This azadibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. |
| | DBCO-Acid Preparation Products And Raw materials |
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