Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
Tel: |
029-81124267 15229202216 |
Email: |
1073@dideu.com |
Products Intro: |
Product Name:Desloratadine Package:25kg
|
Company Name: |
Jigs Chemical Limited
|
Tel: |
+91 80 4290 2764 |
Email: |
info@jigschemical.com |
Products Intro: |
Product Name:Desloratadine
|
|
| "Desloratadine Citrate Disodium" Basic information |
| "Desloratadine Citrate Disodium" Chemical Properties |
Melting point | 150-151°C | storage temp. | -20°C Freezer | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | form | Solid | color | White to Beige |
| "Desloratadine Citrate Disodium" Usage And Synthesis |
Uses | Desloratadine (Loratadine EP Impurity D; Loratadine USP Related Compound A) is an active metabolite of Loratadine (L469575) and used as an oral non-sedating antihistamine to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria (1,2,3). | Clinical Use | Antihistamine: Symptomatic relief of allergy such as hay fever,
urticaria | Drug interactions | Potentially hazardous interactions with other drugs Antivirals: concentration possibly increased by
ritonavir. | Metabolism | Desloratadine is the primary active metabolite of
loratadine. Approximately 40% of the dose is excreted
in the urine and 42% in the faeces over a 10 day period
and mainly in the form of conjugated metabolites.
Approximately 27% of the dose is eliminated in the urine
during the first 24 hours. Less than 1% of the active
substance is excreted unchanged in the active form, as
desloratadine. |
| "Desloratadine Citrate Disodium" Preparation Products And Raw materials |
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