CL 218872 manufacturers
- CL-218872
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- $1.00 / 1KG
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2024-04-15
- CAS:
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1000kg/month
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| | CL 218872 Basic information | | Uses |
| Product Name: | CL 218872 | | Synonyms: | 3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;CL 218872;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;CI 218872;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872 | | CAS: | 66548-69-4 | | MF: | C13H9F3N4 | | MW: | 278.23 | | EINECS: | | | Product Categories: | | | Mol File: | 66548-69-4.mol |  |
| | CL 218872 Chemical Properties |
| Melting point | 193-194 °C(Solv: methanol (67-56-1)) | | density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml | | form | A solid | | pka | 0.48±0.30(Predicted) | | color | Light yellow to brown |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | CL 218872 Usage And Synthesis |
| Uses | CL 218872 is a useful research chemical. CL 218872 is a putative anxiolytic. | | Uses | CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic. | | Definition | ChEBI: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine is a member of pyridazines and a ring assembly. | | Biological Activity | Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo . | | storage | Store at RT |
| | CL 218872 Preparation Products And Raw materials |
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