AH 7614

AH 7614 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:AH-7614;AH 7614
CAS:6326-06-3
Package:1 mL * 10mM (in DMSO);10 mg;100 mg;200 mg;25 mg;5 mg;50 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:AH 7614
CAS:6326-06-3
Purity:0.98 Package:5mg,10mg,100mg,500mg,1g,5g,10g
Company Name: Zibo Hangyu Biotechnology Development Co., Ltd
Tel: +86-0533-2185556 +8617865335152
Email: Mandy@hangyubiotech.com
Products Intro: CAS:6326-06-3
Purity:0.99 Package:5KG;1KG
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:AH-7614
CAS:6326-06-3
Purity:98% Package:$33.9/2mg;$68.9/5mg;$117.9/10mg;$246.9/25mg;$395.9/50mg;$593.9/100mg;$1069.9/200 Remarks:98%
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139
Email: orders@jknbiochem.com
Products Intro: Product Name:AH 7614
CAS:6326-06-3
Purity:0.98 Package:10G:100G
AH 7614 Basic information
Product Name:AH 7614
Synonyms:AH 7614;4-Methyl-N-(9H-xanthen-9-yl)-benzenesulfonamide;Benzenesulfonamide, 4-methyl-N-9H-xanthen-9-yl-;allosteric,linoleic,negative,FFAR,GPR120,FFA4,inhibit,AH7614,AH-7614,NAM,Inhibitor,Free Fatty Acid Receptor,acid
CAS:6326-06-3
MF:C20H17NO3S
MW:351.42
EINECS:
Product Categories:
Mol File:6326-06-3.mol
AH 7614 Structure
AH 7614 Chemical Properties
Melting point 196-197 °C(Solv: ethanol (64-17-5); 1,4-dioxane (123-91-1))
Boiling point 505.9±60.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
storage temp. -20°C (des.)
solubility Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 8 mg/ml with warming).
form solid
pka10.33±0.20(Predicted)
color Off-white
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Safety Information
MSDS Information
AH 7614 Usage And Synthesis
DescriptionAH-7614 (6326-06-3) is a selective antagonist at free fatty acid receptor 4 (FFA4), also known as GPR120. pIC50s= 7.1 and 1.
UsesAH 7614 is a sellective FFAR4 (free fatty acid receptor 4) antagonist which inhibits the intracellular calcium accumilation induced by linoleic acid or FFAR agonists.
in vitroah7614 (0.063, 0.25, and 1μm) blocked linoleic acid and gsk137647a-induced intracellular calcium increase in u2os osteosarcoma cells expressing the ffa4 receptor [1]. in addition, the increase of glucose-stimulated insulin secretion by gsk137647a (50 μm) was abolished in the presence of the selective ffa4 antagonist ah7614 (100 μm) in the min6 mouse insulinoma cell line. moreover, ah7614 (100 μm) blocked gsk137647a (100μm)-mediated a modest increase of glp-1 secretion in the ncih716 cells [1].
targetffa4/gpr120
storageStore at +4°C
References1) Sparks?et al. (2014),?Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120); Bioorg. Med. Chem. Lett.,?24?3100
AH 7614 Preparation Products And Raw materials
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