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Product Name: | MI-463 | Synonyms: | 4-Methyl-5-((4-((6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)meth;MI-463;MI 463;MI463;1628317-18-9;1H-Indole-2-carbonitrile, 4-methyl-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-;MI463,Epigenetic Reader Domain,MI-463,MI 463,Inhibitor,inhibit;4-Methyl-5-((4-((6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)methyl)-1H-indole-2-carbonitrile | CAS: | 1628317-18-9 | MF: | C24H23F3N6S | MW: | 484.54 | EINECS: | | Product Categories: | | Mol File: | 1628317-18-9.mol | ![MI-463 Structure](CAS/GIF/1628317-18-9.gif) |
| MI-463 Chemical Properties |
Boiling point | 663.2±55.0 °C(Predicted) | density | 1.43±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO: soluble; Ethanol: soluble | form | A crystalline solid | pka | 14.56±0.30(Predicted) | color | White to light yellow |
| MI-463 Usage And Synthesis |
Biological Activity | MI-463 is a potent inhibitor of Menin-MLL interaction with IC50 of 15.3 nM. | target | Target | Value | Menin-MLL interaction (Cell-free assay) | 15.3 nM |
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| MI-463 Preparation Products And Raw materials |
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