ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Cyanate ester / isocyanate >(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Suppliers list
Company Name: Jiangsu Yutian pharmaceutical Co.,Ltd.
Tel: +undefined-0518-86098006 +undefined19851887368
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Products Intro: Product Name:(4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:125971-94-0
Purity:99% Package:25kg
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +86 13288715578 +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:125971-94-0
Purity:99% Package:25KG
Company Name: Hangzhou ICH Biofarm Co., Ltd
Tel: +86-0571-28186870; +undefined8613073685410
Email: sales@ichemie.com
Products Intro: Product Name:(4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:125971-94-0
Purity:99% Package:1KG;|20KG;|50KG
Company Name: hebei hongtan Biotechnology Co., Ltd
Tel: +86-86-1913198-3935 +8617331935328
Email: sales03@chemcn.cn
Products Intro: Product Name:(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:125971-94-0
Purity:99% Package:1kg;80USD
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:125971-94-0
Purity:99% Package:100g ;1KG ;5KG 25KG

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate manufacturers

(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Basic information
Product Name:(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms:(4R,6R)-T-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R,6R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R,3R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;tert-Butyl (4R,3R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate;TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXAN-4-YL]ACETATE;(4R,6R)-t-butyl-6-cyanomethyl02,2-dimethyl-1,3-dioxane-4-acetate;(4R-cis)-1,1-dimethylethyl-6-cyanomethyl -2,2-dimethyl-1,3-dloxane-4-acetate;(4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS:125971-94-0
MF:C14H23NO4
MW:269.34
EINECS:425-780-3
Product Categories:INTERMEDIATESOFATORVASTATIN;chiral;(intermediate of atorvastatin);Chemical intermediate for Atorvastatin Calcium;Atorvastatin intermediates;Chiral Building Blocks;Cyanides/Nitriles;Organic Building Blocks
Mol File:125971-94-0.mol
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Structure
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties
Melting point 65-69 °C(lit.)
Boiling point 364.1±17.0 °C(Predicted)
density 1.016±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility soluble in Chloroform
form powder to crystal
color White to Almost white
optical activity[α]20/D 1.0°, c = 1 in chloroform
CAS DataBase Reference125971-94-0(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29329990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
Uses(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
UsesAtorvastatin Intermediate
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials
Preparation Products(3R,5R)-6-Cyano-3,5-dihydroxy-hexanoic Acid tert-Butyl Ester-->Atorvastatin Acetonide tert-Butyl Ester
Tag:(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate(125971-94-0) Related Product Information
Dimethyl fumarate Dimethyl sulfoxide Isobutyl acetate tert-Butanol tert-Butyl chloroacetate tert-Butyl acetate Dimethylbenzylcarbinyl acetate tert-Butyl bromoacetate N,N-Dimethylformamide DL-sec-Butyl acetate Methyl 2,2-dimethylphenylacetate Butyl acetate tert-Butyl peroxyacetate ETHANE (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Atorvastatin calcium Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Atorvastatin