CB-1158 manufacturers
- Numidargistat
-
- $190.00 / 1mg
-
2024-11-18
- CAS:2095732-06-0
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| CB-1158 Basic information |
Product Name: | CB-1158 | Synonyms: | (3R,4S)-1-(L-alanyl)-3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid;INCB01158;3-Pyrrolidinecarboxylic acid, 3-amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-, (3R,4S)-;Numidargistat (CB1158, INCB01158);Numidargistat 2HCl (CB1158, INCB01158);Numidargistat;(3R,4S)-3-Amino-1-[(2S)-2-aminopropanoyl]-4-[3-(dihydroxyboranyl)propyl]pyrrolidine-3-carboxylic acid | CAS: | 2095732-06-0 | MF: | C11H22BN3O5 | MW: | 287.12 | EINECS: | | Product Categories: | pyrolidine | Mol File: | 2095732-06-0.mol | |
| CB-1158 Chemical Properties |
Boiling point | 574.1±60.0 °C(Predicted) | density | 1.299±0.06 g/cm3(Predicted) | pka | 2.13±0.40(Predicted) | form | Solid | color | Off-white to light yellow |
| CB-1158 Usage And Synthesis |
Uses | (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid Dihydrochloride is a salt analog of (3R,4S)-3-Amino-1-[(2S)-2-amino-1-oxopropyl]-4-(3-boronopropyl)-3-pyrrolidinecarboxylic Acid (CAS# 2095732-06-0), which inhibits arginase 1 (Arg1) enzyme and blocks myeloid cell-??mediated immune suppression in the tumor microenvironment. |
| CB-1158 Preparation Products And Raw materials |
|