壳梭孢(菌)素
中文名称 | 壳梭孢(菌)素 |
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中文同义词 | 壳梭孢(菌)素;壳梭孢菌素 来源于扁桃壳梭菌;FUSICOCCIN,真菌化脓毒素 |
英文名称 | FUSICOCCIN |
英文同义词 | FUSICOCCIN;fusicoccin from fusicoccum amygdali;3-[2-(Acetyloxy)-1-methylethyl]-1,2,4,5,6,6a,7,8,9,10a-decahydro-1,5-dihydroxy-9-(methoxymethyl)-6,10a-dimethylcyclopenta[a,d]-dicylo coten-4-yl-6;.alpha.-D-Glucopyranoside, 3-[2-(acetyloxy)-1-methylethyl]-1,2,4,5,6,6A,7,8,9,10A-decahydro-1,5-dihydroxy-9-(methoxymethyl)-6,10A-dimethyldicyclopenta[A,D]cycloocten-4-yl 6-o-(1,1-dimethyl-2-propenyl)-, 3-acetate, [1S-[1.alpha.,3(R*),4.alpha.,5.beta.,6.beta.,6A.alpha.,9.beta.,10A.beta.]]-;Fucicoccin;Nsc113500;Fusicoccin-A (Fusicoccin;α-D-Glucopyranoside, (1S,4R,5R,6R,6aS,9S,10aR)-3-[(1S)-2-(acetyloxy)-1-methylethyl]-1,2,4,5,6,6a,7,8,9,10a-decahydro-1,5-dihydroxy-9-(methoxymethyl)-6,10a-dimethyldicyclopenta[a,d]cycloocten-4-yl 6-O-(1,1-dimethyl-2-propen-1-yl)-, 3-acetate |
CAS号 | 20108-30-9 |
分子式 | C36H56O12 |
分子量 | 680.82 |
EINECS号 | |
相关类别 | Carbohydrates;Carbohydrates A to;Carbohydrates D-FBiochemicals and Reagents;Monosaccharide |
Mol文件 | 20108-30-9.mol |
结构式 | ![]() |
壳梭孢(菌)素 性质
储存条件 | −20°C |
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溶解度 | 可溶于DMSO |
形态 | 白色固体。 |
颜色 | 白色至米白色 |
Fusicoccin (Fusicoccin A) stabilizes a complex between 14-3-3 and the stress response regulator GCN1, inducing GCN1 turnover and neurite outgrowth (EC
50
=29 mM).
Fusicoccin A activates the plasma membrane H
+
-ATPase by stabilizing its binding to 14-3-3 proteins, which results in water loss and the wilting of infected plants. Fusicoccin A decreases the proliferation and migration of human GBM cell lines in vitro, including several cell lines that exhibit varying degrees of resistance to pro-apoptotic stimuli. The IC
50
growth inhibitory concentration of fusicoccin A is 92 µM in the U373-MG cells and 83 µM in the Hs683 glioma cells.
安全信息
WGK Germany | 3 |
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提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/08/19 | HY-122815 | 壳梭孢(菌)素 Fusicoccin | 20108-30-9 | 1mg | 7020元 |