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Diethyl methylmalonate

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Products Intro: Product Name:Diethyl methylmalonate
CAS:609-08-5
Purity:98.5% min Package:200kg
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Products Intro: Product Name:Diethyl methylmalonate
CAS:609-08-5
Purity:99% Package:1KG;10.00;USD
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Products Intro: Product Name:Diethyl methylmalonate
CAS:609-08-5
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Products Intro: Product Name:Diethyl methylmalonate
CAS:609-08-5
Purity:NLT 98% Package:1G;1KG;100KG
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Products Intro: Product Name:Diethyl methylmalonate
CAS:609-08-5
Purity:99% Package:25KG;5KG;1KG

Diethyl methylmalonate manufacturers

  • Diethyl methylmalonate
  • Diethyl methylmalonate pictures
  • $35.00 / 1kg
  • 2024-04-19
  • CAS:609-08-5
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
  • Diethyl methylmalonate
  • Diethyl methylmalonate pictures
  • $0.00 / 200kg
  • 2023-11-01
  • CAS:609-08-5
  • Min. Order: 1kg
  • Purity: 98.5% min
  • Supply Ability: 10tons/month
Diethyl methylmalonate Basic information
Product Name:Diethyl methylmalonate
Synonyms:RARECHEM AL BI 0301;Diethyl methylmalonate 99%;DIETHYL METHYLMALONATE;DIETHYL 2-METHYLPROPANEDIOATE;1,3-Diethyl 2-methylpropanedioate;Diethyl methylmalote;Methoxymalonic Acid Diethyl Ester;Methylmalonic acid diethyl ester~Methylpropanedioic acid diethyl ester
CAS:609-08-5
MF:C8H14O4
MW:174.19
EINECS:210-175-7
Product Categories:Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks;Pharmaceutical Intermediates;Cyanoacetic acid esters;Hydrocyanic acid derivatives;bc0001
Mol File:609-08-5.mol
Diethyl methylmalonate Structure
Diethyl methylmalonate Chemical Properties
Boiling point 198-199 °C (lit.) 78-80 °C/10 mmHg
density 1.022 g/mL at 20 °C (lit.)
refractive index n20/D 1.413(lit.)
Fp 170 °F
storage temp. Sealed in dry,Room Temperature
solubility 1000mg/l
form Liquid
pka13.13±0.46(Predicted)
Specific Gravity1.013
color Clear colorless
PH8 (1000mg/l, H2O, 20℃)
Water Solubility immiscible
BRN 637028
InChIKeyUPQZOUHVTJNGFK-UHFFFAOYSA-N
LogP1.256 (est)
CAS DataBase Reference609-08-5(CAS DataBase Reference)
NIST Chemistry ReferencePropanedioic acid, methyl-, diethyl ester(609-08-5)
EPA Substance Registry SystemPropanedioic acid, methyl-, diethyl ester (609-08-5)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
TSCA Yes
HS Code 29171990
MSDS Information
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Diethyl methylmalonate English
SigmaAldrich English
ACROS English
ALFA English
Diethyl methylmalonate Usage And Synthesis
Chemical Properties Colorless mobile liquid. Slightly soluble in water, soluble in alcohol and oils.
UsesDiethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.
UsesDiethyl methylmalonate is used as intermediate for the syntheses of pharmaceuticals, e.g. non-steroidal anti-inflammatory agents with 2-acrylpropionic acid structures acrylpropionic acid structure. It is also used in the flavour and fragrance industries. Product Data Sheet
General DescriptionDiethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.
Synthesis Diethyl methylmalonate is produced by the following method:1) by condensing Ethylpropionate with Diethyloxalate, followed by heating of the reaction product. 2) from Diethylmalonate plus Sodium and Methyl iodide.
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