- Felodipine
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- $0.00 / 10MG
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2024-09-11
- CAS:86189-69-7
- Min. Order: 10MG
- Purity: ≥98% HPLC
- Supply Ability: 100KG
- FELODIPINE
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- $15.00 / 1KG
-
2021-07-09
- CAS:86189-69-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| Felodipine Basic information |
Product Name: | Felodipine | Synonyms: | 4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINECARBOXYLIC ACID METHYL ESTER;4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID METHYL ESTER;FLODIL;FELODAY;ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;Agon sr;Brn 4331472;Felodipina | CAS: | 86189-69-7 | MF: | C18H19Cl2NO4 | MW: | 384.25 | EINECS: | | Product Categories: | | Mol File: | 86189-69-7.mol | ![Felodipine Structure](CAS/GIF/86189-69-7.gif) |
| Felodipine Chemical Properties |
Hazard Codes | Xn | Risk Statements | 22 | WGK Germany | 3 | RTECS | US7968700 |
| Felodipine Usage And Synthesis |
Uses | Vasodilator. | Brand name | Plendil (AstraZeneca). | Clinical Use | Calcium-channel blocker:HypertensionAngina | Drug interactions | Potentially hazardous interactions with other drugs
Aminophylline and theophylline: possibly increased
aminophylline and theophylline concentration.
Anaesthetics: enhanced hypotensive effect.
Antibacterials metabolism possibly inhibited by
clarithromycin, erythromycin and telithromycin.
Antidepressants: enhanced hypotensive effect with
MAOIs.
Antiepileptics: effect reduced by carbamazepine,
barbiturates, phenytoin and primidone.
Antifungals: metabolism inhibited by itraconazole
and ketoconazole; negative inotropic effect possibly
increased with itraconazole.
Antihypertensives: enhanced hypotensive effect,
increased risk of first dose hypotensive effect of postsynaptic alpha-blockers.
Antivirals: concentration possibly increased by
ritonavir; use with caution with telaprevir.
Grapefruit juice: concentration increased - avoid
concomitant use.
Tacrolimus: possibly increased tacrolimus
concentration | Metabolism | Felodipine is metabolised in the liver and all identified
metabolites are devoid of vasodilating properties.
Approximately 70% of a given dose is excreted as
metabolites in the urine and about 10% with the faeces.
Less than 0.5% of the dose is excreted unchanged in the
urin |
| Felodipine Preparation Products And Raw materials |
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