犬尿氨酸
中文名称 | 犬尿氨酸 |
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中文同义词 | D-2-氨基-4-(2-氨基苯基)-4-氧代丁酸;D-犬尿氨酸;D-2-氨基-4-[2-氨基苯基]-4-氧丁 酸;犬尿氨酸;犬尿氨酸杂质;(R)-2-氨基-4-(2-氨基苯基)-4-氧代丁酸;D-犬尿宁;D-犬尿素 |
英文名称 | D-KYNURENINE |
英文同义词 | D-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID;D-KYNURENINE;D-kynurenine free base;β-Anthraniloyl-D-alanine;R-2-Amino-4-[2-aminophenyl]-4-oxobutanoic acid;REF DUPL: D-Kynurenine;D-Kynurenine sulfate;beta-Anthraniloyl-D-alanine |
CAS号 | 13441-51-5 |
分子式 | C10H12N2O3 |
分子量 | 208.21 |
EINECS号 | |
相关类别 | 化学连接;非天然氨基酸;API intermediates;Amino Acids |
Mol文件 | 13441-51-5.mol |
结构式 | ![]() |
犬尿氨酸 性质
沸点 | 466.6±45.0 °C(Predicted) |
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密度 | 1.343±0.06 g/cm3(Predicted) |
储存条件 | 2-8°C |
溶解度 | 水:5.0(最大浓度 mg/mL);24.01(最大浓度 mM) |
形态 | 结晶固体 |
酸度系数(pKa) | 2.21±0.23(Predicted) |
颜色 | 浅黄至黄色 |
CAS 数据库 | 13441-51-5(CAS DataBase Reference) |
Human Endogenous Metabolite
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D-kynurenine (10, 40, 60, and 100 µM) positively regulates the metastasis of 95D cells, a lung cancer cell line, which is reduced upon siRNAAhr treatment. Significant enhancement VIM expression was detected in the presence of D-kynurenine (10 and 40 µM). 10 µM D-kynurenine markedly attenuates E-cadherin level. 10 µM D-kynurenine-mediated changes of VIM and E-cadherin are substantially attenuated on siRNAAhr treatment as well. The evidences-10/40 µM D-kynurenine-induced up-regulation of CYP1A1, 10 µM D-kynurenine-induced increase of nuclear transfer of Ahr, and 10/40/60/100 µM D-kynurenine-induced enhancement of DER-luciferase activity-indicated that D-kynurenine Is capable of activating Ahr in fact.
安全信息
WGK Germany | 3 |
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海关编码 | 29225000 |
提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-W014502 | 犬尿氨酸 D-Kynurenine | 13441-51-5 | 25mg | 600元 |
2024/08/19 | HY-W014502 | 犬尿氨酸 D-Kynurenine | 13441-51-5 | 10mM * 1mLin Water | 660元 |