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Syntechem Co.,Ltd
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Product Name:(S)-2-aMino-4-(guanidinooxy)butanoic acid CAS:543-38-4 Purity:97% Package:1g;5g;25g;100g;250g;1kg;5kg;10kg;25kg Remarks:we offer low price custom synthesis and contract manufacturing
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L-Canavanine manufacturers
- (L)-Canavanine
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- $1980.00 / 50mg
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2024-10-28
- CAS:543-38-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| L-Canavanine Basic information |
Product Name: | L-Canavanine | Synonyms: | L-Homoserine, O-(aminoiminomethyl)amino-;l-α-amino-γ-(guanidinooxy)-n-butyric acid;2-amino-4-(diaminomethylideneamino)oxy-butanoic acid;L-canavanine free base from jack beans*crystallin;BUTYRICACID,2-AMINO-4-(GUANIDINOOXY)-L-;(+)-O-(Guanidino)-L-homoserine;(S)-2-Amino-4-(guanidinooxy)butyric acid;2-amino-4-(guanidinooxy)butyricacid | CAS: | 543-38-4 | MF: | C5H12N4O3 | MW: | 176.17 | EINECS: | | Product Categories: | | Mol File: | 543-38-4.mol | |
| L-Canavanine Chemical Properties |
Melting point | 184° | alpha | D20 +7.9° (c = 3.2) | Boiling point | 307.78°C (rough estimate) | density | 1.3685 (rough estimate) | refractive index | 1.7900 (estimate) | storage temp. | 2-8°C | solubility | H2O: <100 mg/mL | form | powder | pka | pK1: 2.50(+2);pK2: 6.60(+1);pK3: 9.25(0) (25°C) | PH | 7.93 | optical activity | +7.920 (H2O) |
| L-Canavanine Usage And Synthesis |
Uses | NO synthase inhibitor | Definition | ChEBI: A non-proteinogenicL-alpha-amino acid that is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. Although structurally related to L-arginine, it is non-proteinoge
ic. | Biochem/physiol Actions | Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation. | Purification Methods | Crystallise S-canavanine from absolute EtOH or aqueous EtOH. [Tomiyama J Biol Chem 111 48 1935 gave pK9.25 (COOH), pK 7.4 (guanidinium), pK 11.5 (NH4+), Gulland & Morris J Chem Soc 763 1935,(±) Frankel et al. J Chem Soc 3127 1963, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2622-2628 1961, Beilstein 4 III 1636, 4 IV 3188.] |
| L-Canavanine Preparation Products And Raw materials |
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