| Company Name: |
Amatek Scientific Co. Ltd.
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| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-
CAS:380843-81-2
Purity:97% HPLC Package:5g;25g;100g;1kg
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| Company Name: |
Shenzhen ruikai de biotechnology co., ltd.
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| Tel: |
0755-61348847 17820674378 |
| Email: |
2682116078@qq.com |
| Products Intro: |
Product Name:Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
CAS:380843-81-2
Purity:98%HPLC Package:10mg;25mg;50mg;100mg
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| | Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Basic information |
| | Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Chemical Properties |
| Melting point | 123-125 °C | | Boiling point | 655.4±55.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | pka | 9.19±0.10(Predicted) |
| | Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Usage And Synthesis |
| Uses | Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors. |
| | Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Preparation Products And Raw materials |
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