夫洛丙酮
中文名称 | 夫洛丙酮 |
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中文同义词 | 夫洛丙酮;三羟苯丙酮;2',4',6'-三羟基苯丙酮;6'-三羟基苯丙酮;1-(2,4,6-三羟基苯基)丙-1-酮;2',4',6'-三羟基苯丙酮 |
英文名称 | Flopropione |
英文同义词 | 1-(2,4,6-trihydroxyphenyl)-1-propanon;1-(2,4,6-Trihydroxyphenyl)-1-propanone;13907 R. P.;13907r.p.;Argobroda;Flopropione Phlopropiophenone;1-(2,4,6-trihydroxyphenyl)propanone;1-Propanone, 1-(2,4,6-trihydroxyphenyl)- |
CAS号 | 2295-58-1 |
分子式 | C9H10O4 |
分子量 | 182.17 |
EINECS号 | 218-942-8 |
相关类别 | 小分子抑制剂;中间体-有机中间体;Aromatic Propiophenones (substituted) |
Mol文件 | 2295-58-1.mol |
结构式 | ![]() |
夫洛丙酮 性质
熔点 | 177°C |
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沸点 | 275.56°C (rough estimate) |
密度 | 1.2481 (rough estimate) |
折射率 | 1.4500 (estimate) |
储存条件 | Inert atmosphere,Room Temperature |
溶解度 | 溶于二甲基亚砜 |
形态 | 粉末晶体 |
酸度系数(pKa) | 7.49±0.45(Predicted) |
颜色 | 白色至橙色再至绿色 |
Merck | 14,4106 |
LogP | 2.600 (est) |
CAS 数据库 | 2295-58-1(CAS DataBase Reference) |
NIST化学物质信息 | Flopropione(2295-58-1) |
EPA化学物质信息 | 1-Propanone, 1-(2,4,6-trihydroxyphenyl)- (2295-58-1) |
5-HT 1A Receptor
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COMT
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Flopropione在低于其T (g)温度下表现出无Lorentzian舒张。Flopropione在低于其T (g)温度下比Nifedipine具有更高的分子流动性。 Flopropione在整个温度范围表现出Arrhenius温度依赖性,推断高于T (g)时通过介电弛豫测量的tau(β)与低于T (g)时通过TAM/MDSC测量的tau(β)相一致。
The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.
安全信息
危险类别码 | 36/37/38 |
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安全说明 | 26-36/37/39 |
RTECS号 | UH4429100 |
海关编码 | 2914.50.3000 |