| Company Name: |
Shanghai Sunway Pharmaceutical Technology Co., Ltd
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| Tel: |
021-51613915-820 13611835272 |
| Email: |
mmwang@sunwaypharm.cn |
| Products Intro: |
Product Name:(S)-2-amino-3-(3,4-dihydroxy-phenyl)-propionic acid methyl ester
CAS:7101-51-1
Purity:95% Package:5g; 50g;100g;1kg;10kg
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| | (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Basic information |
| Product Name: | (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER | | Synonyms: | (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER;levodopa methyl ester;DOPA-METHYLESTER;L-DOPA Methyl Ester;(S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride;L-Tyrosine, 3-hydroxy-, Methyl ester;Methyl 3-hydroxy-L-tyrosinate;methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate | | CAS: | 7101-51-1 | | MF: | C10H13NO4 | | MW: | 211.21 | | EINECS: | | | Product Categories: | | | Mol File: | 7101-51-1.mol |  |
| | (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Chemical Properties |
| Boiling point | 350.89°C (rough estimate) | | density | 1.2545 (rough estimate) | | refractive index | 1.5150 (estimate) | | storage temp. | 2-8°C | | form | solid | | pka | 9.67±0.20(Predicted) | | color | White |
| | (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Usage And Synthesis |
| Description | CHF-1301 was launched as an injection in Italy for the treatment of
patients with Parkinson's disease, particularly those with complications in their
clinical responses. CHF-1301 is the methyl ester of L-Dopa (levodopa), the
immediate precursor of dopamine. Thus, this prodrug is more soluble in water at
physiological pH, better absorbed and slowly transformed into levodopa in vivo;
it consequently improves the duration of action and prevents the rapid
fluctuations in response or involontary movements (dyskinesia) observed during chronic treatment with levodopa. In patients with a delayed effect of levodopa
(on-phenomenon) or a severe resistance to L-Dopa (off-phenomenon), CHF-
1301 significantly improves the onset and the stability of the'response. | | Originator | Chiesi Farmaceutici SpA (Italy) | | Definition | ChEBI: Melevodopa is a tyrosine derivative. | | Brand name | Levomet |
| | (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials |
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