| Company Name: |
Beijing Comparison Pharmaceutical Technology Co., Ltd
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| Tel: |
010-010-52878169 15801002657 |
| Email: |
sales@bjcomparison.com |
| Products Intro: |
Product Name:5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
CAS:1187188-60-8
Purity:95% Package:100mg/;50mg/;25mg/;10mg/
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| Company Name: |
ChemStrong Scientific Co.,Ltd
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| Tel: |
0755-0755-66853366 13670046396 |
| Email: |
sales@chem-strong.com |
| Products Intro: |
Product Name:Crisaborole Impurity 37
CAS:1187188-60-8
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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Crisaborole intermediate manufacturers
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| | Crisaborole intermediate Basic information |
| Product Name: | Crisaborole intermediate | | Synonyms: | 5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol;Crisaborole Impurity 59;Crisaborole Impurity 37;Crisaborole Impurity 28;Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]- | | CAS: | 1187188-60-8 | | MF: | C14H13BO4 | | MW: | 256.06 | | EINECS: | | | Product Categories: | | | Mol File: | 1187188-60-8.mol |  |
| | Crisaborole intermediate Chemical Properties |
| Boiling point | 432.1±55.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | pka | 7.05±0.20(Predicted) |
| | Crisaborole intermediate Usage And Synthesis |
| Uses | 5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent. |
| | Crisaborole intermediate Preparation Products And Raw materials |
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