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| Butanilicaine hydrochloride Basic information |
Product Name: | Butanilicaine hydrochloride | Synonyms: | 2-butylamino-6-chloroacet-o-toluidide;butanilicaine;2-(Butylamino)-N-(2-methyl-6-chlorophenyl)acetamide;2-Butylamino-N-(2-chloro-6-methylphenyl)acetamide;2081-65-4 (Phosphate[1:1]);2-Butylamino-6'-chloro-o-acetotoluidide;6027-28-7 (Mono-hydrochloride);Butanilicaina | CAS: | 3785-21-5 | MF: | C13H19ClN2O | MW: | 254.76 | EINECS: | | Product Categories: | | Mol File: | 3785-21-5.mol | |
| Butanilicaine hydrochloride Chemical Properties |
Melting point | 45-46° | Boiling point | bp0.001 145°; bp0.5 166-167° | density | 1.129±0.06 g/cm3(Predicted) | storage temp. | Refrigerator | solubility | DMSO (Slightly), Methanol (Slightly) | form | Solid | pka | 13.41±0.70(Predicted) | color | Pale Brown to Light Brown | NIST Chemistry Reference | Butanilicaine(3785-21-5) |
| Butanilicaine hydrochloride Usage And Synthesis |
Originator | Butanilicaine,Enreco, INC | Uses | Butanilicaine Hydrochloride, is a local anesthetic. | Definition | ChEBI: An amino acid amide amide in which N-butylglycine and 2-chloro-6-methylaniline have combined to form the amide bond; used as a local anaesthetic (amide caine). | Manufacturing Process | To a solution of 4-bromo-2-methylaniline is added 13 g of chloroacetyl
chloride. After the reaction is finished to the mixture id added a solution of 33
g sodium acetate in 138 ml of water. Chloroacetic acid 4-bromo-2-
methylanilide is filtered; yield 24 g, M.P. 135°C (crystallization from ethanol).
20 g of chloroacetic acid 4-bromo-2-methylanilide is dissolved in 200 ml of butylamine. After about 15 hours to the solution is added 2 N hydrochloric
acid. Butylaminoacetic acid 4-bromo-2-methylanilide hydrochloride is removed
by suction and washed with water; yield 90%, M.P. 252-253°C (from
methanol). | Therapeutic Function | Local anesthetic |
| Butanilicaine hydrochloride Preparation Products And Raw materials |
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