| Company Name: |
Hangzhou Sage Chemical Co., Ltd.
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| Tel: |
+86057186818502 13588463833 |
| Email: |
info@sagechem.com |
| Products Intro: |
Product Name:2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-propyl-
CAS:633-47-6
Purity:98% Package:1g;5g;100g;Bulk
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Cropropamide
CAS:633-47-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Carbosynth
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| Tel: |
+86 512 6260 5585 |
| Email: |
sales@carbosynth.com |
| Products Intro: |
Product Name:(E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide
CAS:633-47-6
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| | cropropamide Basic information |
| Product Name: | cropropamide | | Synonyms: | cropropamide;N-[1-[(Dimethylamino)carbonyl]propyl]-N-propyl-2-butenamide;2-ButenaMide, N-[1-[(diMethylaMino)carbonyl]propyl]-N-propyl-;(E)-N-[1-(Dimethylcarbamoyl)propyl]-N-propyl-but-2-enamide | | CAS: | 633-47-6 | | MF: | C13H24N2O2 | | MW: | 240.34 | | EINECS: | 211-193-8 | | Product Categories: | | | Mol File: | 633-47-6.mol |  |
| | cropropamide Chemical Properties |
| Boiling point | bp0.25 128-130° | | density | 0.977±0.06 g/cm3(Predicted) | | storage temp. | Amber Vial, Refrigerator | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Soluble) | | pka | -0.74±0.70(Predicted) | | form | Oil | | color | Pale Yellow to Dark Yellow | | Stability: | Light Sensitive |
| | cropropamide Usage And Synthesis |
| Originator | Cropropamide,Geigy (Novartis) | | Uses | Cropropamide, is the main component of the drug Prethcamide, which is a respiratory stimulant. | | Definition | ChEBI: Cropropamide is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. | | Manufacturing Process | 2-Chlorbutiric acid dimethyl amide are dissolved in absolute benzene and
heated to 110°C with propylamine in the autoclave. After cooling the
propylamine hydrochloride is filtered off, then the benzene solution is treated
with water and freed from any dissolved propylamine hydrochloride by means
of potassium lye. After distillation of the benzene the 2-propylaminobutyric
acid dimethyl amide is rectified in vacuum.
2-Propylaminobutyric acid dimethyl amide is dissolved in benzene and while
cooling, crotonic acid chloride is added and mixed. Then, reaction mixture is
filtered and freed from benzene to give 2-(N-propyl-crotonylamido)butyric acid
dimethyl amide, melting point 128°-130°C. | | Therapeutic Function | Respiratory stimulant |
| | cropropamide Preparation Products And Raw materials |
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