Glutaurine manufacturers
- Glutaurine
-
- $30.00 / 1Box
-
2024-10-18
- CAS:56488-60-9
- Min. Order: 1Box
- Purity: 99.99%
- Supply Ability: 10000000000
|
| | Glutaurine Basic information |
| Product Name: | Glutaurine | | Synonyms: | gamma-L-Glutamyltaurine;gamma-Glutamyltaurine;glutaurin;Litoralon;L-γ-Glutamyltaurine;Nδ-(2-Sulfoethyl)-L-glutamine;γ-Glutamyltaurine;γ-Glu-Tau | | CAS: | 56488-60-9 | | MF: | C7H14N2O6S | | MW: | 254.26 | | EINECS: | | | Product Categories: | | | Mol File: | 56488-60-9.mol |  |
| | Glutaurine Chemical Properties |
| Melting point | 223-226 °C | | density | 1.520±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | DMF: insol; DMSO: 1 mg/ml; Ethanol: insol; PBS (pH 7.2): 5 mg/ml | | form | A solid | | pka | 1.40±0.50(Predicted) | | color | White to off-white | | Water Solubility | Water : 125 mg/mL (491.62 mM; Need ultrasonic) |
| | Glutaurine Usage And Synthesis |
| Uses | Glutaurine has been observed to display antiepileptic effects with anti-amnesia properties. Mimics anxiolytic drug Diazepam (D416855). | | Definition | ChEBI: Glutaurine is a dipeptide resulting from the formal condensation of the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was initially found in the parathyroid in 1980 and later in the brain of mammals. It has a role as a mouse metabolite, a mammalian metabolite, a human metabolite, an anticonvulsant, an anxiolytic drug and a hormone. It is a L-glutamine derivative, a sulfonic acid and a dipeptide. It is functionally related to a taurine. It is a tautomer of a glutaurine zwitterion. | | in vivo | Glutaurine (1, 10, 20 or 50 μg/rat; p.o.) significantly restores the latency of entry in both the 24 and 48 hours tests at the dose of 50 μg/rat[2].
Glutaurine (100~3000 ug/kg; i.p.) significantly reduces T3 blood levels in a dose-dependent manner, but does not significantly raise T4 blood levels[3]. | Animal Model: | CFY male rats (170~250g)[2] | | Dosage: | 1, 10, 20 or 50 μg/rat | | Administration: | P.o. | | Result: | Significantly restored the latency of entry in both the 24 and 48 h tests at the dose of 50 μg/rat.
|
| Animal Model: | Fischer 344 rats[3] | | Dosage: | 100~3000 ug/kg | | Administration: | I.p. | | Result: | Significantly reduced T3 blood levels in a dose-dependent manner, but did not significantly raise T4 blood levels.
|
|
| | Glutaurine Preparation Products And Raw materials |
|