| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Zoloperone;Zoloperone
CAS:52867-74-0
Purity:98% Package:5 mg
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| Company Name: |
United States Biological
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| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:Zoloperone
CAS:52867-74-0
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| Company Name: |
Chempro Tech Co., Ltd.
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| Tel: |
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| Email: |
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| Products Intro: |
Product Name:4-(4-fluorophenyl)-5-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)oxazol-2(3H)-one
CAS:52867-74-0
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| | Zoloperone Basic information |
| Product Name: | Zoloperone | | Synonyms: | 4-(4-Fluorophenyl)-5-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-4-oxazolin-2-one;4-(4-Fluorophenyl)-5-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]oxazol-2(3H)-one;4-(4-fluorophenyl)-5-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)oxazol-2(3H)-one;Zoloperone;LR 511;2(3H)-Oxazolone, 4-(4-fluorophenyl)-5-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-;Zoloperonum | | CAS: | 52867-74-0 | | MF: | C22H24FN3O3 | | MW: | 397.448 | | EINECS: | | | Product Categories: | | | Mol File: | 52867-74-0.mol |  |
| | Zoloperone Chemical Properties |
| Toxicity | LD50 intraperitoneal in mouse: > 2gm/kg |
| | Zoloperone Usage And Synthesis |
| Originator | Zoloperone,ZYF Pharm Chemical | | Manufacturing Process | To 20% solution of phosgene in toluene, agitated and cooled to 0°C, are
added over 30 min a solution of 1-p-fluoro-benzoyl-1-hydroxy-3-N-[N'-(2-
methoxyphenyl)]piperazinopropane and triethylamine in anhydrous
chloroform. It is agitated at ambient temperature for 5 h, cooled to 0°C and
the solution saturated with gaseous ammonia. The solution is agitated at
ambient temperature for 3 h, filtered and the filtrate dried under reduced
pressure, 4-ρ-fluorophenyl-5-β-(4-o-methoxyphenylpiperazino)ethyl-4-
oxazolin-2-one, melting point 154°C (by alcohol) was obtained. | | Therapeutic Function | Neuroleptic |
| | Zoloperone Preparation Products And Raw materials |
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