| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:N-(α-Linolenoyl) Tyrosine
CAS:259143-19-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
Jiangsu Hongmin Pharmaceutical Co., Ltd.
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| Tel: |
18221292452 |
| Email: |
fannieliu@glschina.com |
| Products Intro: |
Product Name:N-(L-Tyrosine)-9z,12z,15z-Octadecatrienamide
CAS:259143-19-6
Purity:0.95 Package:g;kg
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:N-(α-Linolenoyl) Tyrosine
CAS:259143-19-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE
CAS:259143-19-6
Purity:98% Package:100mg (solution); 10mg (solution); 5mg (solution); 50mg (solution) Remarks:Medbio
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:N-(α-Linolenoyl) Tyrosine;N (α Linolenoyl) Tyrosine,N(αLinolenoyl) Tyrosine
CAS:259143-19-6
Purity:98% Package:100 mg
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| | N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Basic information |
| Product Name: | N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE | | Synonyms: | N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE;N-(ALPHA-LINOLEOYL) TYROSINE;NALT;N-(α-Linolenoyl) Tyrosine;DEQLZTQITSWABQ-GMOGWPNXSA-N;N-(.alpha.-Linolenoyl) Tyrosine;L-Tyrosine, N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-;N-(α-Linolenoyl) Tyrosine | | CAS: | 259143-19-6 | | MF: | C27H39NO4 | | MW: | 441.6 | | EINECS: | | | Product Categories: | | | Mol File: | 259143-19-6.mol |  |
| | N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml |
| | N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Usage And Synthesis |
| Description | Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.1 N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.2 In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.2 | | Definition | ChEBI: N-(alpha-Linolenoyl) Tyrosine is a tyrosine derivative. | | References | 1. Martin, J.B. Molecular basis of the neurodegenerative disorders N. Engl. J. Med. 340(25),1970-1980(1999).
2. Yehuda, S. Possible anti-Parkinson properties of N-(α-linolenoyl) tyrosine: A new molecule Pharmacol. Biochem. Behav. 72(1-2),7-11(2002). |
| | N(L-TYROSINE)-9Z,12Z,15Z-OCTADECATRIENAMIDE Preparation Products And Raw materials |
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