| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Alinastine
CAS:154541-72-7
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
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alinastine manufacturers
- Alinastine
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- $2500.00 / 100mg
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2024-10-28
- CAS:154541-72-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | alinastine Basic information |
| Product Name: | alinastine | | Synonyms: | alinastine;1H-Benzimidazole, 2-[1-[2-[4-(1,1-dimethylethyl)phenyl]ethyl]-4-piperidinyl]-1-(2-ethoxyethyl)- | | CAS: | 154541-72-7 | | MF: | C28H39N3O | | MW: | 433.636 | | EINECS: | | | Product Categories: | | | Mol File: | 154541-72-7.mol |  |
| | alinastine Chemical Properties |
| Boiling point | 574.2±50.0 °C(Predicted) | | density | 1.07±0.1 g/cm3(Predicted) | | pka | 8.78±0.10(Predicted) |
| | alinastine Usage And Synthesis |
| Originator | Alinastine ,Fabrica Espanola de
Productos Quimicos y
Farmaceuticos | | Manufacturing Process | 1.5 g of a sodium hydride suspension in oil are added to another suspension
of 10.83 g of 2-[1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidin-4-yl]-1Hbenzimidazole
in 150 ml of dimethylformamide and the mixture is stirred for 1
h at room temperature, then a solution of 2-(2-ethoxyethyl)tosylate in
dimethylformamide are slowly added. The mixture is heated at 60°C for 16 h,
poured onto water and extracted with ether. The extracts are washed with
water, dried over anhydrous sodium sulfate and concentrated. The obtained oil
is purified by column chromatography yielding 6.0 g of 1-(2-ethoxyethyl)-2-
[1-(2-(4-(1,1-dimethylethyl)phenyl)ethyl)piperidine-4-yl]-1H-benzimidazole,
melting point 138°-140°C. | | Therapeutic Function | Antihistaminic, Antiallergic |
| | alinastine Preparation Products And Raw materials |
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