- Thiomorpholine-1,1-dioxide
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- $5.00 / 1KG
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2024-04-11
- CAS:39093-93-1
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: g-kg-tons, free sample is available
- Thiomorpholine-1,1-dioxide
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- $15.00 / 1Kg/Bag
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2023-04-12
- CAS:39093-93-1
- Min. Order: 1Kg/Bag
- Purity: 99.8%
- Supply Ability: Weekly supply of 1000KG
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| | Thiomorpholine-1,1-dioxide Basic information |
| Product Name: | Thiomorpholine-1,1-dioxide | | Synonyms: | THIOMORPHOLINE DIOXIDE;TIMTEC-BB SBB010267;1,1-DIOXIDE-4-THIOMORPHOLINE;Thiomorpholine-1,1-oxide;thiomorpholine 1,1-dioxide(SALTDATA: HCl);ThioMorpholine-1,1-dioxid;1$l^{6},4-thioMorpholine-1,1-dione;1,1-DioxidothioMorpholine | | CAS: | 39093-93-1 | | MF: | C4H9NO2S | | MW: | 135.18 | | EINECS: | 815-944-6 | | Product Categories: | Heterocycles series | | Mol File: | 39093-93-1.mol |  |
| | Thiomorpholine-1,1-dioxide Chemical Properties |
| Melting point | 0°C | | Boiling point | 0°C | | density | 1.239±0.06 g/cm3(Predicted) | | Fp | 0°C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 6.48±0.20(Predicted) | | color | White to Off-White | | InChI | InChI=1S/C4H9NO2S/c6-8(7)3-1-5-2-4-8/h5H,1-4H2 | | InChIKey | NDOVLWQBFFJETK-UHFFFAOYSA-N | | SMILES | N1CCS(=O)(=O)CC1 | | CAS DataBase Reference | 39093-93-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | HS Code | 2934999090 |
| | Thiomorpholine-1,1-dioxide Usage And Synthesis |
| Chemical Properties | light yellow solid | | Uses | Thiomorpholine 1,1-Dioxide is a useful building block, used in the synthetic preparation of antibacterial biaryloxazolidinone analogues, and isothiazolo-pyridine derivatives for use as cyclin G-associated kinase inhibitors and antiviral agents. | | Synthesis |
To a solution of tert-butylthiomorpholine-4-carboxylate (5.8 g, 0.024 mol) in dichloromethane (50 ml) was added trifluoroacetic acid (70 ml), and the resulting mixture was stirred at 25°C. 5 hours until TLC showed the reaction was complete. Concentrate under reduced pressure to obtain a mixture. Water (30 mL) was added to the mixture, the mixture was basified to pH=8.0 with aqueous ammonia solution, and the mixture was extracted three times with dichloromethane (50 mLx3). The organic extracts were combined and washed with water and brine. The organic extract was dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated under reduced pressure to obtain Thiomorpholine 1,1-dioxide.
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| | Thiomorpholine-1,1-dioxide Preparation Products And Raw materials |
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