| Company Name: |
Huida Medical Technology (Shanghai) Co., LTD Gold
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| Tel: |
13601750004 |
| Email: |
lizhi@pharoschem.com |
| Products Intro: |
Product Name:(S)-2-(tert-butyldimethylsilyloxy)propanal
CAS:87727-28-4
Purity:95+ Package:5KG;1KG
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(S)-2-(tert-Butyldimethylsilyloxy)propanal manufacturers
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| | (S)-2-(tert-Butyldimethylsilyloxy)propanal Basic information |
| Product Name: | (S)-2-(tert-Butyldimethylsilyloxy)propanal | | Synonyms: | (S)-2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PROPIONALDEHYDE;Propanal, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2S)-;(S)-2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PRO;(S)-2-(tert-Butyldimethylsilyloxy)propanal | | CAS: | 87727-28-4 | | MF: | C9H20O2Si | | MW: | 188.34 | | EINECS: | | | Product Categories: | | | Mol File: | 87727-28-4.mol |  |
| | (S)-2-(tert-Butyldimethylsilyloxy)propanal Chemical Properties |
| Boiling point | 67-68 °C(Press: 14 Torr) | | density | 0.868±0.06 g/cm3(Predicted) | | InChI | InChI=1S/C9H20O2Si/c1-8(7-10)11-12(5,6)9(2,3)4/h7-8H,1-6H3/t8-/m0/s1 | | InChIKey | YMIIHJBTQLZXBV-QMMMGPOBSA-N | | SMILES | C(=O)[C@@H](O[Si](C(C)(C)C)(C)C)C |
| | (S)-2-(tert-Butyldimethylsilyloxy)propanal Usage And Synthesis |
| storage | Inert atmosphere,Store in freezer, under -20C | | Synthesis | Ethyl ester 3 (4.00 g, 17.2 mmol) was added to diethyl ether (70 mL) and cooled to -78 °C. DIBAL-H (1M in hexane, 20 mmol, 20 mL) was added cautiously dropwise over 1 h. The solution was stirred for a further 4 h at -78 °C before being quenched with MeOH (40 mL) and warmed to room temperature. Saturated potassium sodium tartrate solution (60 mL) was added and the mixture was left to stir for 12 h before being extracted with diethyl ether (3 x 15 mL). The organic extracts were dried with MgSO4, filtered, and concentrated under reduced pressure to give the crude (S)-2-(tert-Butyldimethylsilyloxy)propanal (3.22 g, 99%) as a clear oil.
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| | (S)-2-(tert-Butyldimethylsilyloxy)propanal Preparation Products And Raw materials |
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