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| | Tetrabutylammonium fluoride trihydrate Basic information |
| | Tetrabutylammonium fluoride trihydrate Chemical Properties |
| Melting point | 62-63 °C(lit.) | | Fp | -17℃ | | storage temp. | Store below +30°C. | | form | Crystalline Powder, Crystals and/or Chunks | | Specific Gravity | 0.887 | | color | White to slightly yellow | | PH | pH (50g/l, 25℃) : 5.0～8.0 | | Water Solubility | SOLUBLE | | Sensitive | Hygroscopic | | BRN | 3761900 | | Exposure limits | ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3 | | InChI | InChI=1S/C16H36N.FH.H2O/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;;/h5-16H2,1-4H3;1H;1H2/q+1;;/p-1 | | InChIKey | UQCWXKSHRQJGPH-UHFFFAOYSA-M | | SMILES | [N+](CCCC)(CCCC)(CCCC)CCCC.[F-].O | | CAS DataBase Reference | 87749-50-6(CAS DataBase Reference) |
| | Tetrabutylammonium fluoride trihydrate Usage And Synthesis |
| Description | Tetrabutylammonium fluoride trihydrate is a commonly used salt within the realms of organic chemistry and biochemistry. This compound is employed as a potent base, finding extensive use in diverse applications, including organic compound synthesis, buffer preparation, and protein purification. It plays a pivotal role in the synthesis of various organic compounds, such as carboxylic acids, amines, and alcohols. Additionally, this compound facilitates the purification of nucleic acids, including DNA and RNA. Acting as a strong base, tetrabutylammonium fluoride trihydrate possesses the ability to deprotonate a wide range of organic compounds. It is commonly used in applications such as preparation of deprotecting agents, synthesis of lipophilic peprides during DNA transfections, and many more. | | Chemical Properties | white crystals or crystalline powder | | Uses | Reactant for:
Preparation of deprotecting agents in preparation of cellulose derivatives
Synthesis of lipophilic peptides for DNA transfections in vivo
Dehydrobromination reactions | | General Description | Tetrabutylammonium fluoride trihydrate is a mild base used in reactions like aldol-type condensation reactions, Michael-type reactions, ring-opening reactions. Its is also used as a promoter in cross-coupling reactions and cyclization of carbocycles and heterocycles. |
| | Tetrabutylammonium fluoride trihydrate Preparation Products And Raw materials |
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