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| | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Basic information |
| Product Name: | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one | | Synonyms: | (2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one;(2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib);(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one;(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one;Nilotinib IMpurity ((2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one);Imatinib EP Impurity A (Nilotinib Impurity 16);Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one | | CAS: | 123367-26-0 | | MF: | C10H12N2O | | MW: | 176.22 | | EINECS: | | | Product Categories: | | | Mol File: | 123367-26-0.mol |  |
| | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties |
| Melting point | 113℃ | | Boiling point | 281℃ | | density | 1.070 | | Fp | 124℃ | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 4.74±0.70(Predicted) | | color | Dark Brown to Very Dark Brown |
| | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Usage And Synthesis |
| Description | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is a pharmaceutical intermediate used as an intermediate of nilotinib, a targeted anticancer drug for the treatment of chronic myeloid leukaemia (CML). | | Uses | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents. | | Solubility in organics | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is soluble in chloroform and dichloromethane. |
| | (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials |
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