10-乙酰基-3,7-二羟基吩嗪
中文名称 | 10-乙酰基-3,7-二羟基吩嗪 |
---|---|
中文同义词 | 10-乙酰基-3,7-二羟基吩嗪;1-(3,7-二羟基-10H-吩恶嗪-10-基)乙酮;荧光底物-10-乙酰基-3,7-二羟基吩嗪;10-乙酰基-3;7-二羟基吩噁嗪;荧光红染料;AMPLITEADHP过氧化物和过氧化酶荧光探针*相当于AMPLEX RED*;10-乙酰基-3,7-二羟基吩噁嗪 |
英文名称 | 10-ACETYL-3,7-DIHYDROXYPHENOXAZINE |
英文同义词 | AMPLEX(R) RED REAGENT;10-ACETYL-3,7-DIHYDROXYPHENOXAZINE;10-ACETYL-3,7-DIHYDROXYPHENOXAZINE [ADHP];10-ACETYL-3,7-DIHYDROXYPHENOXAZINE,99%;10-Acetyl-3,7-dihydroxypenoxazin;Amplisyn Red, 99%;1-(3,7-Dihydroxy-10H-phenoxazin-10-yl)ethanone;ADHP [10-Acetyl-3,7-dihydroxyphenoxazine], [Known as Amplex Red, TM of Molecular probes] |
CAS号 | 119171-73-2 |
分子式 | C14H11NO4 |
分子量 | 257.24 |
EINECS号 | |
相关类别 | 酶底物;自有品牌试剂;荧光染料;试剂盒-细胞分析试剂盒;合成材料中间体;小分子;探针 |
Mol文件 | 119171-73-2.mol |
结构式 |
10-乙酰基-3,7-二羟基吩嗪 性质
熔点 | >250 °C (decomp) |
---|---|
沸点 | 618.6±55.0 °C(Predicted) |
密度 | 1.459±0.06 g/cm3(Predicted) |
储存条件 | 2-8°C |
溶解度 | DMF:25mg/mL; DMSO:25mg/mL; DMSO:PBS (pH 7.2)1:5:0.15 mg/ml;乙醇:1.5mg/mL |
形态 | 结晶固体 |
酸度系数(pKa) | 9.41±0.20(Predicted) |
颜色 | 浅棕色至棕色 |
To obtain the parameters K m and k cat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H 2 O 2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a K m of 31±4 μM and the k cat of 186± 6 s −1 .The k obs also increases over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second order rate constant obtain from the slope of k obs against ADHP concentration K app on is 2.1±0.2 mM/s.
提供商 | 语言 |
---|---|
英文
|
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/04/30 | HY-101880 | ADHP | 1 mg | 300元 | |
2024/04/30 | HY-101880 | 10-乙酰基-3,7-二羟基吩嗪 ADHP | 119171-73-2 | 5mg | 850元 |