- (S)-(+)-Glycidyl Phthalimide
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- $8.00 / 1kg
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2024-04-23
- CAS:161596-47-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| (S)-(+)-Glycidyl Phthalimide Basic information |
| (S)-(+)-Glycidyl Phthalimide Chemical Properties |
Melting point | 102 °C | Boiling point | 347.4±15.0 °C(Predicted) | density | 1.446±0.06 g/cm3(Predicted) | vapor pressure | 0.001-2.17Pa at 25-90.25℃ | refractive index | 10 ° (C=2.2, CHCl3) | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | pka | -2.24±0.20(Predicted) | form | Solid | color | White | InChI | InChI=1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1 | InChIKey | DUILGEYLVHGSEE-ZETCQYMHSA-N | SMILES | C1(=O)C2=C(C=CC=C2)C(=O)N1C[C@H]1CO1 | LogP | 1.2 at 40℃ |
Hazard Codes | Xi | Risk Statements | 41 | Safety Statements | 26-39 | WGK Germany | 2 | HS Code | 29252900 |
| (S)-(+)-Glycidyl Phthalimide Usage And Synthesis |
Chemical Properties | White powder | Uses | (S)-(+)-Glycidyl Phthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500). It is also a key intermediate of rivaroxaban. | Synthesis | Phthalimide and (S)-1-substituent propylene oxide are used as raw materials, a reaction occurs under the action of a catalyst to generate 2-((S)-3-substituent-2-hydroxypropyl isodihydroindole-1,3-dione, and finally (S)-glycidyl phthalimide is generated by means of a ring-closure reaction.
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| (S)-(+)-Glycidyl Phthalimide Preparation Products And Raw materials |
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