Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
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3bsc@sina.com |
Products Intro: |
Product Name:DCB;[(3-Chlorophenyl)Methylene]hydrazone-3-chlorobenzaldehyde CAS:6971-97-7 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
BOC Sciences
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Tel: |
1-631-485-4226; 16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:DCB CAS:6971-97-7 Purity:98% by HPLC Remarks:DCB is an allosteric ligand for the metabotropic glutamate receptor mGlu5 that displays neutral modulation. It inhibits the modulation of mGlu5 by other allosteric modulators without affecting agonist
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
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info@emmx.com |
Products Intro: |
Product Name:DCB CAS:6971-97-7 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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Product Name: | DCB | Synonyms: | NSC 67224;[(3-CHLOROPHENYL)METHYLENE]HYDRAZONE-3-CHLOROBENZALDEHYDE;3,3'-DICHLOROBENZALDAZINE;3,3μ-Dichlorobenzaldazine, NSC 67224;1,1'-(Azinobismethylidyne)bis(3-chlorobenzene);1,2-Bis(3-chlorobenzylidene)hydrazine;3,3'-Dichlorobenzylideneazine;α,α'-Azinobis(m-chlorotoluene) | CAS: | 6971-97-7 | MF: | C14H10Cl2N2 | MW: | 277.15 | EINECS: | | Product Categories: | Glutamate receptor | Mol File: | 6971-97-7.mol | |
Melting point | 40 °C | Boiling point | 387.8±42.0 °C(Predicted) | density | 1.21±0.1 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | DMSO: ~6.8 mg/mL | form | solid | pka | 5.84±0.50(Predicted) | color | yellow |
Uses | DCB is an allosteric ligand for mGluR-5 (1). Regulates glutamate concentration however may induce neuronal damage through cerebral ischemia (2). | Biological Activity | Allosteric ligand for the metabotropic glutamate receptor mGlu 5 ; displays neutral modulation. Does not affect agonist-stimulated mGlu 5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB ([(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde ) and DMeOB ([(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde ). |
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