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| | 4-Fluoro-3-nitrobenzoic acid Basic information |
| | 4-Fluoro-3-nitrobenzoic acid Chemical Properties |
| Melting point | 123-126 °C (lit.) | | Boiling point | 92°C 15mm | | density | 1.5071 (estimate) | | Fp | 92°C/15mm | | storage temp. | Sealed in dry,Room Temperature | | solubility | 95% ethanol: soluble50mg/mL, clear, light yellow | | pka | 3.54±0.10(Predicted) | | form | Powder or Crystals | | color | Light yellow to tan | | Water Solubility | insoluble | | BRN | 2107562 | | CAS DataBase Reference | 453-71-4(CAS DataBase Reference) | | NIST Chemistry Reference | 4-Fluoro-3-nitrobenzoic acid(453-71-4) |
| | 4-Fluoro-3-nitrobenzoic acid Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 4-Fluoro-3-nitrobenzoic acid was used:
- as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity
- in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure
- in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction
- in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones
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| | 4-Fluoro-3-nitrobenzoic acid Preparation Products And Raw materials |
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