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| Product Name: | BQ-788 | | Synonyms: | BQ-788 SODIUM;BQ-788 SYNTHETIC >97% ETB ENDOTHELIN REC EPT;N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucinesodiumsalt;1-ELAIDYLPHOSPHOCHOLINE, >97%;N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine sodium salt, 2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle;N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-;DMpc-gaMMa-MeLeu-D-Trp(1-CO2CH3)-D-Nle.Na (DMpc : cis-2,6-DiMethylpiperidinocarbonyl);2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle | | CAS: | 156161-89-6 | | MF: | C34H52N5NaO7 | | MW: | 665.81 | | EINECS: | | | Product Categories: | Endothelin receptor | | Mol File: | 156161-89-6.mol |  |
| | BQ-788 Chemical Properties |
| storage temp. | -20°C | | solubility | acetonitrile: 0.3 mg/mL | | form | solid | | color | white |
| | BQ-788 Usage And Synthesis |
| Uses | BQ-788 has been used as a selective endothelin-B (ETRB) blocker in human airway smooth muscle cells (HASMCs), uterine mesothelial cells (UtMCs)-derived vascular smooth muscle cells (VSMCs), and human umbilical vein endothelial cells (HUVECs) | | Biological Activity | Potent, selective ET B receptor antagonist (IC 50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells). | | Biochem/physiol Actions | Selective ETB endothelin receptor antagonist. | | storage | +4°C |
| | BQ-788 Preparation Products And Raw materials |
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