| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Exo1;2-[(4-Fluorobenzoyl)aMino]-benzoicacidMethylester
CAS:461681-88-9
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Ascent Scientific
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| Tel: |
4401179829988 |
| Email: |
customerservice@ascentscientific.co.uk |
| Products Intro: |
Product Name:Exo-1
CAS:461681-88-9
Purity:>99% Package:10mg;50mg Remarks:Vesicular trafficking inhibitor
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Exo1
CAS:461681-88-9
Purity:99% by HPLC Remarks:Exo1 is a reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Exo1 releases ADP-ribosylation factor (ARF)1 from Golgi and disrupts the functions of Golgi.
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| Product Name: | EXO1 | | Synonyms: | EOX 1;EXOCYTIC INHIBITOR 1;EXO1;4-FLUORO-BZ-2-ABZ-OME;2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE;Anti-EXO1, N-Terminal antibody produced in rabbit;Exonuclease 1 | | CAS: | 461681-88-9 | | MF: | C15H12FNO3 | | MW: | 273.26 | | EINECS: | | | Product Categories: | Signalling | | Mol File: | 461681-88-9.mol |  |
| Melting point | 132-134℃ | | Boiling point | 415.2±45.0 °C(Predicted) | | density | 1.246±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | DMSO: 19 mg/mL, soluble | | form | solid | | pka | -1.09±0.10(Predicted) |
| Uses | Exo1 is used in the synthetic preparation of tricyclic heterocyclic compounds as antagonists of tachykinin receptor (substance P receptor) for prevention and/or treatment of substance P-related diseases. | | Definition | ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides. | | Biological Activity | Reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC 50 ~ 20 mM). Has similar, but not identical, action to brefeldin A (1,6,7,8,9,11ab,12,13,14,14aa-Decahydro-1b,13a-dihydroxy-6b-methyl-4H-cyclopent(f)oxacyclotridecin-4-one ). |
| | EXO1 Preparation Products And Raw materials |
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