| Company Name: |
VDM Biochemicals
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| Tel: |
0330-2528181 |
| Email: |
sales@vdmbio.com |
| Products Intro: |
Product Name:VEGFR Tyrosine Kinase Inhibitor II
CAS:269390-69-4
Purity:>=98% by HPLC Package:110USD/5mg
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:VEGFR Tyrosine Kinase Inhibitor II
CAS:269390-69-4
Purity:98% Package:1G;10G;100G Remarks:VEGFR tyrosine kinase inhibitor II is a pyridinyl-anthranilamide compound that potently inhibits the kinase activities of VEGFR2 (KDR), VEGFR1 (FLT1), and c-Kit (IC50 = 20, 180, and 240 nM, respective
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| | N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Basic information |
| | N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Chemical Properties |
| Boiling point | 463.6±40.0 °C(Predicted) | | density | 1.331±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml | | form | A crystalline solid | | pka | 12.62±0.70(Predicted) | | color | White to off-white |
| | N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Usage And Synthesis |
| Uses | VEGFR Tyrosine Kinase Inhibitor II is an agent that potently inhibits kinase activities of KDR, Flt-1 and c-Kit. | | Biological Activity | Cell permeable: yes', 'Primary Target
Kinase activities of KDR, Flt-1 and c-Kit', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 20 nM, 180 nM and 240 nM against kinase activities of KDR, Flt-1 and c-Kit, respectively | | IC 50 | KDR: 0.02 μM (IC50); Flt-1: 0.18 μM (IC50); EGFR: 0.24 μM (IC50) |
| | N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Preparation Products And Raw materials |
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