Company Name: |
LGM Pharma
|
Tel: |
1-(800)-881-8210 |
Email: |
inquiries@lgmpharma.com |
Products Intro: |
Product Name:DexverapaMil CAS:38321-02-7 Purity:Typically NLT 98%
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Company Name: |
Clearsynth Labs Limited
|
Tel: |
+91-22-26355700 |
Email: |
info@clearsynth.com |
Products Intro: |
Product Name:R(+)-VERAPAMIL CAS:38321-02-7 Remarks:CS-AC-39466
|
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Email: |
marketing@energy-chemical.com |
Products Intro: |
Product Name:(R)-(+)-VerapamilHydrochloride CAS:38321-02-7 Purity:NULL Package:1mg;2.5mg Remarks:NULL
|
Company Name: |
QUALITY CONTROL SOLUTIONS LTD.
|
Tel: |
0755-66853366; 13670046396 |
Email: |
ORDERS@QCSRM.COM |
Products Intro: |
Product Name:Verapamil Impurity 33 CAS:38321-02-7 Purity:95% HPLC Package:10MG;25MG;50MG;100MG
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(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile manufacturers
- Dexverapamil
-
- $2500.00 / 100mg
-
2024-10-24
- CAS:38321-02-7
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Basic information |
Product Name: | (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile | Synonyms: | Dexverapamil;(aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile;Dexverapami;Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (aR)- (9CI);Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (R)-;d-Verapamil;(aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile Hydrochloride;Dexverapamil Hydrochloride | CAS: | 38321-02-7 | MF: | C27H38N2O4 | MW: | 454.61 | EINECS: | 253-878-4 | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | Mol File: | 38321-02-7.mol | |
| (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Chemical Properties |
Melting point | 129-131°C | Boiling point | 586.1±50.0 °C(Predicted) | density | 1.058±0.06 g/cm3(Predicted) | pka | 8.97±0.50(Predicted) |
| (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Usage And Synthesis |
Chemical Properties | Off-White Solid | Uses | Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells | Definition | ChEBI: A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby p
tentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil. |
| (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Preparation Products And Raw materials |
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